Morita Lucas H J, Ferreira Vitor H, Crestani Carlos E
Federal Institute of Education, Science and Technology of São Paulo (IFSP), R. Stefano D'Avassi, 625, Matao, São Paulo 15991-502, Brazil.
ACS Omega. 2025 Mar 14;10(11):10911-10917. doi: 10.1021/acsomega.4c08835. eCollection 2025 Mar 25.
Extractive distillation is widely used in industries such as anhydrous ethanol manufacturing. History shows several problems related to separation agents, such as chloroform, cyclohexane, ethyl ether, carbon tetrachloride, and ethylene acetate. Environmental agencies have restricted the use of several solvents. There is an opening for research into less toxic and more effective dehydrating agents. Both glycerol and fructose are potential separation agents; glycerol has not proven viable for commercial operation to date, and fructose, despite its potential demonstrated in the literature, has the limitation of adding a solid to the top of a distillation column. Hence, glycerol is intended to add fructose to the extractive distillation column, which makes it necessary to know the solubility of fructose in glycerol. This work addresses new experimental data on fructose solubility in glycerol for temperatures ranging from (308.15 to 351.15) K, together with a fit with Nývlt Equation and thermodynamic modeling of the equilibrium, which are essential for predicting the quaternary equilibrium of water, ethanol, fructose, and glycerol. The study of extractive distillation for producing anhydrous ethanol using glycerol and fructose as extracting agents has great potential for application in the industry, as demonstrated by the studies carried out so far.
萃取精馏在无水乙醇制造等行业中广泛应用。历史表明，在分离剂方面存在若干问题，例如氯仿、环己烷、乙醚、四氯化碳和乙酸乙烯酯。环境机构已限制了几种溶剂的使用。因此，开展毒性更低且更有效的脱水剂研究具有可行性。甘油和果糖均为潜在的分离剂；截至目前，甘油尚未被证明适用于商业运营，而果糖尽管在文献中展现出了潜力，但存在向精馏塔顶添加固体的局限性。因此，计划在萃取精馏塔中添加果糖，这就需要了解果糖在甘油中的溶解度。本文给出了果糖在甘油中于（308.15至351.15）K温度范围内溶解度的新实验数据，以及与尼尔特方程的拟合结果和平衡的热力学模型，这些对于预测水、乙醇、果糖和甘油的四元平衡至关重要。到目前为止的研究表明，以甘油和果糖作为萃取剂生产无水乙醇的萃取精馏研究在工业上具有巨大的应用潜力。
