肠致病性大肠杆菌（EPEC）导致一名成年人出现慢性腹泻和低钠血症。
Enteropathogenic (EPEC) Causes Chronic Diarrhea and Hyponatremia in an Adult.
作者信息
Chen Saisai, Feuille Colin
机构信息
Department of Medicine University of California San Francisco San Francisco California USA.
Division of Gastroenterology, Department of Medicine University of California San Francisco San Francisco California USA.
出版信息
Clin Case Rep. 2025 Mar 27;13(4):e70288. doi: 10.1002/ccr3.70288. eCollection 2025 Apr.
Abstract
Enteropathogenic (EPEC) is frequently identified on gastrointestinal pathogen multiplex polymerase chain reaction testing. However, it is unclear whether EPEC causes diarrhea in adults. We describe the case of a 48-year-old man living in the United States who presented with 6 weeks of large-volume watery diarrhea and significant hyponatremia refractory to hypertonic saline and fluid restriction, who was found to have EPEC. Ciprofloxacin was initiated, resulting in the resolution of both diarrhea and hyponatremia. This case demonstrates that EPEC can be pathogenic in adults and can be associated with significant hyponatremia.
摘要
肠道致病性大肠杆菌（EPEC）在胃肠道病原体多重聚合酶链反应检测中经常被发现。然而，EPEC是否会导致成人腹泻尚不清楚。我们描述了一名居住在美国的48岁男性病例，他出现了6周的大量水样腹泻和严重低钠血症，对高渗盐水和液体限制治疗无效，最终被发现感染了EPEC。开始使用环丙沙星治疗后，腹泻和低钠血症均得到缓解。该病例表明，EPEC在成人中可能具有致病性，并可能与严重低钠血症有关。
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