Naylor G R, Bartels E M, Bridgman T D, Elliott G F
Biophys J. 1985 Jul;48(1):47-59. doi: 10.1016/S0006-3495(85)83759-0.
Collins and Edwards (1971, Am. J. Physiol., 221:1130-1133) have shown that a tissue potential can be measured with microelectrodes in glycerinated muscle and that this potential is consistent with a Donnan equilibrium of small ions due to the concentration of net fixed electric charge on the contractile proteins. This approach has been combined with x-ray and light diffraction measurements of the muscle lattice dimensions, and the data are used to determine the thick filament charge and thin filament charge under a variety of different conditions. The thick filament charge is a function of the bathing solution, in particular its pH and ionic composition. These parameters are important in determining the volume of the equilibrium lattice and possibly are involved in the contraction mechanism itself.
柯林斯和爱德华兹（1971年，《美国生理学杂志》，221:1130 - 1133）已经表明，可以用微电极在甘油处理过的肌肉中测量组织电位，并且这种电位与由于收缩蛋白上净固定电荷的浓度而导致的小离子唐南平衡相一致。这种方法已与肌肉晶格尺寸的X射线和光衍射测量相结合，这些数据被用于确定在各种不同条件下粗肌丝电荷和细肌丝电荷。粗肌丝电荷是浴液的函数，特别是其pH值和离子组成。这些参数在确定平衡晶格的体积方面很重要，并且可能参与收缩机制本身。
