Urakov A L, Baranov A G, Sutiagin S P, Odiiankov E G, Ipatova E N
Biull Eksp Biol Med. 1985 Jul;100(7):19-21.
It has been established that tissue cooling to 15-20 degrees C brings about a short-term spasm of smooth muscles of the intestine, peripheral vessels and of the visceral vessels, replaced by an appreciable spasmolytic effect at the 5th-8th minute of hypothermia. The maximal hyperemia develops by the 15th-20th minute of the cooling and persists over the whole period of the cooling. It is assumed that inhibition of oxidative phosphorylation in the mitochondria of the smooth muscles underlies the spasmolytic action of cold. In addition, cold produces a marked hypocoagulation effect.
已经证实，将组织冷却至15-20摄氏度会导致肠道、外周血管和内脏血管的平滑肌出现短期痉挛，在体温过低的第5-8分钟会被明显的解痉作用所取代。最大充血在冷却的第15-20分钟出现，并在整个冷却期间持续存在。据推测，平滑肌线粒体中氧化磷酸化的抑制是寒冷解痉作用的基础。此外，寒冷会产生明显的低凝作用。
