Raj Jalem Spurgeon, Usharani Purimitla
Department of Emergency medicine and critical care, Bliss Hospital, Murad Nagar Road, Mehidipatnam, Hyderabad - 500028, Telangana, India.
Department of Microbiology, Dr. Patnam Mahender Reddy Institute of Medical Sciences, Chevella, Ranga Reddy, Telangana, India.
Bioinformation. 2024 Nov 30;20(11):1619-1622. doi: 10.6026/9732063002001619. eCollection 2024.
Wound healing is a complex process involving multiple stages to restore the integrity and function of damaged tissues. Researchers are exploring the therapeutic potential of HOCl in treating infections and inflammatory conditions, given its efficacy in killing pathogens and modulating immune responses. The present study is a prospective study aimed to know the wound healing nature of HOCl on open wounds in patients attending out-patient department. The study was conducted for a period of one year Jan 2023 to Jan 2024 at Bliss Hospital, Hyderabad, Telangana district, India. Hypochlorous acid (Vida solutions, Pvt. Ltd) was used to irrigate the open wound. Among the 10 reported cases, three were females and seven were males. Most of the cases were reported from middle-age and old-age persons except one paediatric case of age 3 years a female girl. A male patient of age 72 years with co-morbidities diabetes and hypertension suffering with chronic wound on left leg for a period of 35 years because of thorn prick injury. The complete wound healing took nearly 15 weeks in this patient. The wound healing takes place 8 to 15 weeks maximum in all the 10 cases and the above findings concluded that, these features lead to a stabilized HOCl solution as an ideal wound care agent.
伤口愈合是一个复杂的过程,涉及多个阶段以恢复受损组织的完整性和功能。鉴于次氯酸在杀灭病原体和调节免疫反应方面的功效,研究人员正在探索其在治疗感染和炎症性疾病方面的治疗潜力。本研究是一项前瞻性研究,旨在了解次氯酸对门诊患者开放性伤口的愈合作用。该研究于2023年1月至2024年1月在印度特伦甘纳邦海得拉巴市的布利斯医院进行了一年。使用次氯酸(Vida solutions,私人有限公司)冲洗开放性伤口。在报告的10例病例中,3例为女性,7例为男性。除1例3岁女童的儿科病例外,大多数病例来自中年和老年患者。一名72岁的男性患者患有糖尿病和高血压等合并症,因荆棘刺伤左腿患有慢性伤口长达35年。该患者的伤口完全愈合花费了近15周时间。在所有10例病例中,伤口愈合最长需要8至15周,上述研究结果表明,这些特性使次氯酸溶液成为一种理想的伤口护理剂。