Flemming A F, Ruggins N
Br J Plast Surg. 1985 Jul;38(3):432-4. doi: 10.1016/0007-1226(85)90260-7.
Only two cases of malignant melanoma in childhood have previously been reported in this Journal (Olbourne and Harrison, 1974; Keall et al., 1981). The report describing 31 cases in the Manchester area (Pratt et al., 1981) indicates that this condition may be more common in this country than previously supposed. A case of malignant melanoma arising in a mole in a 23 month male child is reported. A review of the literature shows that there are no survival figures for cases without metastasis but at present there is no reason to suspect that the disease is any less aggressive than in adults. It cannot be stressed too often that any mole with rapid growth, ulceration, bleeding with minimal trauma and change in colour should be biopsied urgently irrespective of the age of the patient.
此前本刊仅报道过两例儿童恶性黑色素瘤病例（奥尔本和哈里森，1974年；基尔等人，1981年）。描述曼彻斯特地区31例病例的报告（普拉特等人，1981年）表明，这种疾病在该国可能比以前认为的更为常见。本文报告了一例发生于一名23个月大男童痣内的恶性黑色素瘤。文献回顾显示，尚无无转移病例的生存数据，但目前没有理由怀疑该疾病的侵袭性比成人低。必须再三强调，任何出现快速生长、溃疡、轻微创伤后出血及颜色改变的痣，无论患者年龄大小，都应紧急进行活检。
