Zhou H Y, Zhang J, Weng D D
Department of Respiratory and Critical Care Medicine, Yuyao People's Hospital, Yuyao 315400, China.
Department of Infectious Diseases, Yuyao People's Hospital, Yuyao 315400, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2025 Mar 20;43(3):237-240. doi: 10.3760/cma.j.cn121094-20240109-00008.
This paper analyzed the clinical data of a patient with recurrent infection of chlamydia psittaci pneumonia within 7 months. The patient had a clear history of contact with live poultry, and the clinical manifestations were dry cough, persistent fever, and respiratory failure. Chest CT imaging changes showed lobar consolidation of infected lung lobes, ground-glass shadows, bronchial air-filling signs, and pleural effusion. The two infections were detected in bronchoalveolar lavage fluid by metagenomic next-generation sequencing (mNGS) and pathogen targeted next-generation sequencing (tNGS), respectively, to achieve early diagnosis of chlamydia psittaci pneumonia. New tetracycline drugs were used as the core of treatment for both infections, and rapid improvement was achieved after anti-infection treatment.
本文分析了1例7个月内鹦鹉热衣原体肺炎反复感染患者的临床资料。该患者有明确的活禽接触史，临床表现为干咳、持续发热及呼吸衰竭。胸部CT影像改变显示感染肺叶实变、磨玻璃影、支气管充气征及胸腔积液。分别通过宏基因组二代测序（mNGS）和病原体靶向二代测序（tNGS）在支气管肺泡灌洗液中检测到这两次感染，以实现鹦鹉热衣原体肺炎的早期诊断。两次感染均采用新型四环素类药物作为治疗核心，抗感染治疗后病情迅速好转。
