Liu Wenting, Li Wengao, Deng Lili, Luo Xian, Tan Yibing, Xiang Jiagen, Wu Yan, Hu Yanan, Sun Hengwen, Yang Yuan
School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, China.
Department of Psychiatry, General Hospital of Southern Theatre Command, Guangzhou, China.
BMC Nurs. 2025 Mar 31;24(1):352. doi: 10.1186/s12912-025-02964-7.
Family caregivers of breast cancer patients often experience significant psychological challenges, including depression, anxiety, and fear of cancer recurrence (FCR), yet these issues receive insufficient attention. This study aims to explore the heterogeneity of FCR among family caregivers and identify distinct subgroups based on their FCR levels.
A cross-sectional survey was conducted with 866 family caregivers of breast cancer patients at two tertiary hospitals in Guangzhou, Guangdong Province. All participants completed the Fear of Cancer Recurrence Scale (FCR-7), the Patient Health Questionnaire (PHQ-9), and the Generalized Anxiety Scale (GAD-7) to assess their levels of FCR, depression, and anxiety. Latent class analysis (LCA) was used to identify subgroups of FCR, and multiple logistic regression analyses were performed to explore factors influencing FCR.
Three distinct subgroups of FCR were identified: low FCR group (16.17%), moderate FCR group (13.16%), and high FCR group (70.67%). Predictors of higher FCR included lower income, higher anxiety, and higher depression levels.
Family caregivers of breast cancer patients exhibit varying levels of FCR, with significant predictors being income, anxiety, and depression. Targeted interventions (e.g., psychoeducation, stress management, mindfulness exercises, and cognitive-behavioral therapy) that address these factors may help improve the mental health and well-being of family caregivers.
乳腺癌患者的家庭照顾者常常面临重大的心理挑战，包括抑郁、焦虑以及对癌症复发的恐惧（FCR），然而这些问题并未得到足够的关注。本研究旨在探讨家庭照顾者中FCR的异质性，并根据他们的FCR水平确定不同的亚组。
在广东省广州市的两家三级医院对866名乳腺癌患者的家庭照顾者进行了横断面调查。所有参与者均完成了癌症复发恐惧量表（FCR-7）、患者健康问卷（PHQ-9）和广泛性焦虑量表（GAD-7），以评估他们的FCR、抑郁和焦虑水平。采用潜在类别分析（LCA）来确定FCR的亚组，并进行多元逻辑回归分析以探讨影响FCR的因素。
确定了三个不同的FCR亚组：低FCR组（16.17%）、中度FCR组（13.16%）和高FCR组（70.67%）。较高FCR的预测因素包括较低的收入、较高的焦虑和较高的抑郁水平。
乳腺癌患者的家庭照顾者表现出不同水平的FCR，重要的预测因素是收入、焦虑和抑郁。针对这些因素的有针对性的干预措施（如心理教育、压力管理、正念练习和认知行为疗法）可能有助于改善家庭照顾者的心理健康和幸福感。
