Jiang Guozheng, Wang Shuyang, Xu Luchun, Li Zeyu, Feng Ningning, Qiu Ziye, Yang Yongdong, Yu Xing
Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Front Bioeng Biotechnol. 2025 Mar 17;13:1533088. doi: 10.3389/fbioe.2025.1533088. eCollection 2025.
Screw loosening is a common complication following lumbar spine fixation surgery, yet the biomechanical outcomes after screw loosening remain rarely reported. This study aims to utilize finite element (FE) models to compare the biomechanical performance of PEEK rod dynamic fixation and titanium rod rigid fixation in the postoperative lumbar spine, exploring potential biomechanical mechanisms for re-stabilization of loosened screws.
A FE model of the lumbar spine from L3 to the sacrum was developed using CT image segmentation. Four L4-S1 fixation models were constructed: PEEK rod dynamic fixation (PEEK model), titanium rod rigid fixation (titanium model), PEEK rod with pedicle screw loosening (PEEK-PSL model), and titanium rod with pedicle screw loosening (titanium -PSL model). A preload of 300 N was applied to the superior surface of L3. Stress distributions in the intervertebral discs, facet joints, pedicle screws, and rods were calculated to evaluate the biomechanical effects of different fixation methods.
Across four physiological loading conditions, the stress differences in intervertebral discs, facet joints, and nucleus pulposus between the PEEK model and titanium model were minimal. However, vertebral body stress was significantly higher in the PEEK model, whereas screw and rod stresses were greater in the titanium model. Screw loosening further increased stress in all models. The S1 screw in the PEEK-PSL model exhibited lower and more uniform stress, while stress was concentrated at the screw-rod junction in the titanium-PSL model.
The PEEK rod fixation system demonstrated superior stress distribution, reducing stress concentration risks and improving stability while minimizing screw loosening rates. In contrast, the titanium rod system offers advantages in scenarios requiring high rigidity, potentially making it more suitable for patients with greater stability needs.
螺钉松动是腰椎固定手术后的常见并发症,但螺钉松动后的生物力学结果鲜有报道。本研究旨在利用有限元(FE)模型比较聚醚醚酮(PEEK)棒动态固定和钛棒刚性固定在术后腰椎中的生物力学性能,探索松动螺钉重新稳定的潜在生物力学机制。
使用CT图像分割技术建立从L3到骶骨的腰椎有限元模型。构建了四个L4-S1固定模型:PEEK棒动态固定(PEEK模型)、钛棒刚性固定(钛模型)、带椎弓根螺钉松动的PEEK棒(PEEK-PSL模型)和带椎弓根螺钉松动的钛棒(钛-PSL模型)。在L3上表面施加300 N的预载荷。计算椎间盘、小关节、椎弓根螺钉和棒中的应力分布,以评估不同固定方法的生物力学效应。
在四种生理加载条件下,PEEK模型和钛模型之间椎间盘、小关节和髓核的应力差异最小。然而,PEEK模型中的椎体应力明显更高,而钛模型中的螺钉和棒应力更大。螺钉松动进一步增加了所有模型中的应力。PEEK-PSL模型中的S1螺钉应力较低且分布更均匀,而钛-PSL模型中的应力集中在螺钉-棒交界处。
PEEK棒固定系统表现出优异的应力分布,降低了应力集中风险,提高了稳定性,同时使螺钉松动率降至最低。相比之下,钛棒系统在需要高刚性的情况下具有优势,可能使其更适合稳定性需求较高的患者。