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基于贝宁六家参考医院的回顾性研究分析新生儿感染的患病率及决定因素

Prevalence and determinants of neonatal infections in Benin based on a retrospective study in six reference hospitals.

作者信息

Kounou Arielle, Koudokpon Hornel, Sintondji Kevin, Lègba Boris, Fabiyi Kafayath, Yadouléton Anges, Saarinen Susanne, Dougnon Victorien

机构信息

Research Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, Benin.

Viral Hemorrhagic Fevers and Arboviruses Laboratory, Ministry of Health, Benin, Cotonou, Benin.

出版信息

Sci Rep. 2025 Apr 1;15(1):11093. doi: 10.1038/s41598-025-94442-y.

Abstract

Maternal and neonatal infections pose a significant public health challenge, particularly in developing countries like Benin. This retrospective study investigates the frequency and determinants of maternal and neonatal infections in Benin during 2022, utilizing data from six reference hospitals. The study includes 123 neonates suspected of infection, analyzing factors such as birth weight, breastfeeding practices, clinical delivery parameters, and laboratory-confirmed infection rates. Findings reveal that 32% of suspected cases were confirmed infections, with a higher prevalence among premature newborns and those born in specific hospitals. The study emphasizes the need for improved diagnostic facilities, infection control practices, and awareness among healthcare workers and pregnant women. Recommendations for future research include broader geographic coverage and enhanced training programs.

摘要

孕产妇和新生儿感染构成了重大的公共卫生挑战,在贝宁这样的发展中国家尤为如此。这项回顾性研究利用来自六家参考医院的数据,调查了2022年贝宁孕产妇和新生儿感染的频率及决定因素。该研究纳入了123名疑似感染的新生儿,分析了出生体重、母乳喂养方式、临床分娩参数和实验室确诊感染率等因素。研究结果显示,32%的疑似病例被确诊感染,早产新生儿以及在特定医院出生的新生儿感染率更高。该研究强调需要改善诊断设施、感染控制措施,提高医护人员和孕妇的意识。对未来研究的建议包括扩大地理覆盖范围和加强培训项目。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb0e/11962093/d66a9b4dd8eb/41598_2025_94442_Fig1_HTML.jpg

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