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急诊科患者中同时存在非法芬太尼使用和精神障碍的情况。

Co-occurring illicit fentanyl use and psychiatric disorders in emergency department patients.

作者信息

Downs Allie, Walter Lauren, Shelton Richard, Li Li

机构信息

Department of Psychiatry and Behavioral Neurobiology, Heersink School of Medicine, University of Alabama at Birmingham, 1720 University Blvd, Birmingham, AL, 35294, USA.

Department of Emergency Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.

出版信息

Sci Rep. 2025 Apr 1;15(1):11192. doi: 10.1038/s41598-025-92311-2.

Abstract

This paper sought to describe the characteristics of emergency department (ED) patients with illicit fentanyl use and concurrent psychiatric disorders, as studies within this population of patients is limited. ED patients with a fentanyl-positive urine drug screen were identified, and patient characteristics, medical histories, and test results were extracted. Among the fentanyl positive drug screens of ED patients, the majority were between the ages of 25 and 44, male, white, and uninsured. Additionally, more than one third of these patients had concurrent psychiatric disorders with mood disorders being the most prevalent, followed by psychotic disorders. Patients with co-occurring psychiatric disorders were found to have higher rates of marijuana use, repeat ED visits and/or hospital admissions at six months, and more admissions to psychiatry inpatient settings compared to those patients without co-occurring psychiatric disorders. Concurrent other substance use and rates of buprenorphine prescribing at discharge were not different between the groups; however, rates of naloxone provision at discharge were lower in patients with co-occurring psychiatric disorders. This cohort demonstrates higher healthcare recidivism and utilization.

摘要

本文旨在描述使用非法芬太尼并伴有精神疾病的急诊科(ED)患者的特征,因为针对这一患者群体的研究有限。识别出尿液药物筛查芬太尼呈阳性的急诊科患者,并提取患者特征、病史和检测结果。在急诊科患者芬太尼阳性药物筛查中,大多数患者年龄在25至44岁之间,为男性、白人且未参保。此外,这些患者中超过三分之一患有并发精神疾病,其中情绪障碍最为普遍,其次是精神障碍。与没有并发精神疾病的患者相比,患有并发精神疾病的患者大麻使用率更高,六个月内急诊复诊和/或住院率更高,且入住精神科住院病房的次数更多。两组之间其他物质的并发使用率和出院时丁丙诺啡的处方率没有差异;然而,患有并发精神疾病的患者出院时纳洛酮的提供率较低。这一队列显示出更高的医疗累犯率和利用率。

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