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对来自BariPredict队列的减肥手术候选人的饮食失调风险及风险相关因素进行横断面分析。

Cross-sectional analysis of eating disorder risk and risk correlates in candidates for bariatric surgery from the BariPredict cohort.

作者信息

AlTarrah Dana, Al-Abdullah Lulwa, Alhusayan Mohammed, Canha Dulce, Almazeedi Sulaiman, Al-Serri Ahmad, Abulhasan Maryam, Alsomly Talia, Almutawa Naif, Al-Onaizi Mohammed, Fagherazzi Guy, Alzaid Fawaz

机构信息

Department of Social and Behavioral Science, Faculty of Public Health, Kuwait University, Kuwait City, Kuwait.

Dasman Diabetes Institute, Gulf Road intersecting Jassim Al Bahar St., Sharq, Block 3, Dasman, P.O. Box 1180, Kuwait City, Kuwait.

出版信息

Sci Rep. 2025 Apr 1;15(1):11191. doi: 10.1038/s41598-025-95614-6.

Abstract

Bariatric surgery is an effective intervention for managing obesity. Persons with obesity are a high-risk population for eating disorders (ED), and these can negatively impact perioperative and long-term outcomes of surgery. We aim to understand prevalence and correlates of ED in preintervention patients, identifying those needing psychological support. Baseline cross-sectional analysis of 275 patients of the BariPredict cohort (NCT06480058), a study to assess predictors of long-term surgery outcomes. Psychological assessments were conducted using SCOFF, KUAS, and BDI tools. Data were analyzed for prevalence of high ED risk and for associations of clinical, biological and demographic factors. Mean age was 38.5 years, mean BMI was 42.3 kg/m², with 62.5% being female. 65.8% of patients had a SCOFF score ≥ 2 indicating high ED risk. Class II obesity (p < 0.05), younger age (p < 0.01), and higher depression (p < 0.01) were associated with ED risk in a logistic regression adjusted for age, obesity class, diabetes, HbA1c, depression and anxiety scores. We report high preintervention prevalence of ED, with a risk profile corresponding to BMI of 35-39.9 Kg/m in younger adults with concurrent depression. This patient profile should be prioritized for psychological assessment and support to potentially improve outcomes of bariatric surgery.

摘要

减重手术是治疗肥胖症的一种有效干预措施。肥胖者是饮食失调(ED)的高危人群,而饮食失调会对手术围手术期及长期预后产生负面影响。我们旨在了解干预前患者中饮食失调的患病率及其相关因素,确定那些需要心理支持的患者。对BariPredict队列(NCT06480058)的275例患者进行基线横断面分析,该研究旨在评估手术长期预后的预测因素。使用SCOFF、KUAS和BDI工具进行心理评估。分析数据以了解饮食失调高风险的患病率以及临床、生物学和人口统计学因素之间的关联。平均年龄为38.5岁,平均体重指数为42.3kg/m²,其中62.5%为女性。65.8%的患者SCOFF评分≥2,表明饮食失调风险高。在对年龄、肥胖等级、糖尿病、糖化血红蛋白、抑郁和焦虑评分进行逻辑回归调整后,II级肥胖(p<0.05)、较年轻的年龄(p<0.01)和较高的抑郁程度(p<0.01)与饮食失调风险相关。我们报告干预前饮食失调的患病率较高,在同时患有抑郁症的年轻成年人中,风险特征与体重指数为35-39.9 Kg/m²相对应。应优先对这一患者群体进行心理评估和支持,以潜在改善减重手术的预后。

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