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单光子发射计算机断层扫描/计算机断层扫描(SPECT/CT)与三相骨扫描:一种用于确定全膝关节置换术后不明原因前膝痛患者二次髌骨表面置换指征的有价值的诊断方法。

SPECT/CT and triple-phase bone scan: A valuable diagnostic approach for identifying indications for secondary patellar resurfacing in patients with unexplained anterior knee pain post-TKA.

作者信息

Wu Chuanlong, Wang Hongyi, Chen Zhijie, Zhang Jiong, Liu Zhihong, Feng Jianmin, Jiang Xufeng, He Chuan

机构信息

Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

Department of Nuclear Medicine, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

出版信息

Arthroplasty. 2025 Apr 2;7(1):15. doi: 10.1186/s42836-025-00300-7.

Abstract

OBJECTIVE

The efficacy of secondary patellar resurfacing (SPR) in alleviating anterior knee pain (AKP) following total knee arthroplasty (TKA) remains uncertain. The purpose of this study was to assess the suitability of SPR using single photon emission computed tomography/computed tomography (SPECT/CT) in conjunction with triple-phase bone scan (TPBS).

METHODS

We performed a retrospective analysis on a prospectively-enrolled cohort of patients suffering from AKP in the context of TKA. In this cohort, we identified a subset of 17 patients (involving 18 knees), who had unexplained AKP and were potential candidates for secondary patellar resurfacing (SPR). The candidates for SPR were designated the experimental group, and subjects receiving other forms of treatment were referred to as the Control group. The selection for these treatment options was based on the findings from SPECT/CT and triple-phase bone scan (TPBS). Data collection spanned from preoperative to postoperative follow-up periods and encompassed basic demographics, preoperative findings of SPECT/CT plus TPBS, and Knee Society Score (KSS).

RESULTS

SPECT/CT and TPBS revealed focal radionuclide concentration in the patella in 12 patients (13 knees) and in other locations in 5 patients (5 knees) with unexplained AKP, complementing the findings from medical history and physical examinations. The Experimental group showed signs of patellar maltracking or early-stage patellofemoral osteoarthritis (OA) following TKA and received SPR treatment. Postoperatively, the objective knee indicators score was significantly higher than preoperative scores (88.46 ± 5.77 vs. 76.38 ± 7.64, P < 0.05). Similarly, the functional activities score was significantly improved postoperatively (74.31 ± 6.68 vs. 50.46 ± 9.01, P < 0.05). Patient satisfaction score was substantially elevated after SPR (33.38 ± 2.87 vs. 17.08 ± 5.69, P < 0.05). The control group mainly included patients who experienced loosening, periprosthetic joint infection (PJI), or instability. These patients received revision surgeries tailored to their individual pathologies and postoperative follow-ups showed favorable outcomes.

CONCLUSIONS

SPECT/CT in combination with TPBS may serve as a valuable tool for assessing the suitability of SPR for the post-TKA management of unexplained AKP. Video Abstract.

摘要

目的

全膝关节置换术(TKA)后二次髌骨表面置换术(SPR)缓解膝前痛(AKP)的疗效仍不确定。本研究的目的是评估使用单光子发射计算机断层扫描/计算机断层扫描(SPECT/CT)联合三相骨扫描(TPBS)来评估SPR的适用性。

方法

我们对一组前瞻性纳入的TKA术后患有AKP的患者队列进行了回顾性分析。在该队列中,我们确定了17例患者(涉及18个膝关节)的亚组,这些患者患有无法解释的AKP,是二次髌骨表面置换术(SPR)的潜在候选者。SPR的候选者被指定为实验组,接受其他形式治疗的受试者被称为对照组。这些治疗方案的选择基于SPECT/CT和三相骨扫描(TPBS)的结果。数据收集涵盖术前至术后随访期,包括基本人口统计学、术前SPECT/CT加TPBS的结果以及膝关节协会评分(KSS)。

结果

SPECT/CT和TPBS显示,12例患者(13个膝关节)髌骨有局灶性放射性核素浓聚,5例患者(5个膝关节)在其他部位有无法解释的AKP,补充了病史和体格检查的结果。实验组在TKA后出现髌骨轨迹不良或早期髌股骨关节炎(OA)迹象,并接受了SPR治疗。术后,客观膝关节指标评分显著高于术前评分(88.46±5.77对76.38±7.64,P<0.05)。同样,术后功能活动评分也显著改善(74.31±6.68对50.46±9.01,P<0.05)。SPR后患者满意度评分大幅提高(33.38±2.87对17.08±5.69,P<0.05)。对照组主要包括经历假体松动、假体周围关节感染(PJI)或不稳定的患者。这些患者接受了针对其个体病理情况的翻修手术,术后随访显示效果良好。

结论

SPECT/CT联合TPBS可作为评估SPR对TKA术后无法解释的AKP管理适用性的有价值工具。视频摘要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac0d/11963298/79767554006f/42836_2025_300_Fig1_HTML.jpg

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