Mohammadi Abdolreza, Asgari Fardin, Yar Ehsan Zemanati, Rezayat Mina, Najarzadegan Mahdi, Kazem Aghamir Seyed Mohammad
Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Case Rep Med. 2025 Mar 25;2025:7440806. doi: 10.1155/carm/7440806. eCollection 2025.
This case report presents a rare instance of synchronous adrenal ganglioneuroma and an ipsilateral retroperitoneal mass in a 51-year-old woman with episodic hypertensive crises and increased symptom frequency. Imaging revealed a hypodense mass near the right kidney and an additional adrenal mass, which led to surgical intervention. Laboratory findings indicated hypercortisolism, and both masses were surgically removed by the laparoscopy approach. Postoperative pathology identified both masses as maturing-type ganglioneuroma, with no signs of malignancy or complications. This case highlights the diagnostic and therapeutic challenges of such rare presentations and emphasizes the importance of detailed imaging, surgical excision, and histopathological analysis. The potential link between elevated cortisol levels and ganglioneuroma, as observed here, underscores the need for further research into these benign tumors.
本病例报告展示了一名51岁女性罕见的同步发生肾上腺神经节细胞瘤和同侧腹膜后肿块的情况，该患者有发作性高血压危象且症状频率增加。影像学检查发现右肾附近有一个低密度肿块以及另一个肾上腺肿块，这促使了手术干预。实验室检查结果显示皮质醇增多症，两个肿块均通过腹腔镜手术切除。术后病理检查确定两个肿块均为成熟型神经节细胞瘤，无恶性迹象或并发症。本病例突出了此类罕见表现的诊断和治疗挑战，并强调了详细影像学检查、手术切除和组织病理学分析的重要性。此处观察到的皮质醇水平升高与神经节细胞瘤之间的潜在联系，凸显了对这些良性肿瘤进行进一步研究的必要性。
