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肾小管囊性肾细胞癌:病例报告及文献综述

Tubulocystic renal cell carcinoma: Case report and literature review.

作者信息

Ding Yun-Shen, Wang Yi-Han, Liu Feng

机构信息

Department of Urology, The Sixth People's Hospital South Campus Affiliated to Shanghai Jiaotong University, Shanghai, China.

出版信息

Urol Case Rep. 2025 Jan 29;59:102965. doi: 10.1016/j.eucr.2025.102965. eCollection 2025 Mar.

DOI:10.1016/j.eucr.2025.102965
PMID:40171229
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11959878/
Abstract

To optimize the diagnosis and treatment of Tubulocystic renal cell carcinoma, we present our experience with a case of it and review the literature. Tubulocystic renal cell carcinoma (TRCC) is a rare subtype of renal carcinoma with distinctive histological and molecular characteristics. This study provides a comprehensive analysis of TRCC, focusing on its pathological features, diagnostic criteria, and potential molecular mechanisms. The findings highlight the unique histological architecture and biological behavior of TRCC, distinguishing it from other renal cell carcinomas. Advanced imaging techniques and molecular biomarkers play a pivotal role in its accurate diagnosis.

摘要

为优化肾小管囊性肾细胞癌的诊断和治疗,我们介绍一例该疾病的诊治经验并回顾相关文献。肾小管囊性肾细胞癌(TRCC)是一种罕见的肾癌亚型,具有独特的组织学和分子特征。本研究对TRCC进行了全面分析,重点关注其病理特征、诊断标准和潜在分子机制。研究结果突出了TRCC独特的组织结构和生物学行为,使其有别于其他肾细胞癌。先进的成像技术和分子生物标志物在其准确诊断中发挥着关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93cb/11959878/33b09b1bdbe4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93cb/11959878/33b09b1bdbe4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93cb/11959878/33b09b1bdbe4/gr1.jpg

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本文引用的文献

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Multimodal imaging findings of tubulocystic renal cell carcinoma: A case report.肾小管囊性肾细胞癌的多模态影像学表现:一例报告
J Clin Imaging Sci. 2024 Sep 30;14:37. doi: 10.25259/JCIS_93_2024. eCollection 2024.
2
Tubulocystic renal cell carcinoma: A case report of rare tumor.肾小管囊性肾细胞癌:一例罕见肿瘤病例报告
Radiol Case Rep. 2024 Aug 13;19(11):4836-4840. doi: 10.1016/j.radcr.2024.07.094. eCollection 2024 Nov.
3
Fumarate Hydratase-Deficient Renal Cell Carcinoma With Predominant Tubulocystic Features Mimics Tubulocystic Renal Cell Carcinoma.
琥珀酸脱氢酶缺陷型肾细胞癌伴主型小管囊状结构特征酷似小管囊状肾细胞癌。
Arch Pathol Lab Med. 2024 Dec 1;148(12):1358-1364. doi: 10.5858/arpa.2023-0330-OA.
4
Durable Response to Pazopanib in a Patient with Fumarate Hydratase-Mutant Tubulocystic Renal Cell Carcinoma.一名富马酸水合酶突变型肾小管囊性肾细胞癌患者对帕唑帕尼的持久反应
Case Rep Oncol. 2023 Apr 14;16(1):234-242. doi: 10.1159/000528697. eCollection 2023 Jan-Dec.
5
Tubulocystic Renal Cell Carcinoma: An Underrecognized Clinicopathologic Entity.肾小管囊性肾细胞癌:一种未被充分认识的临床病理实体。
Ochsner J. 2022 Summer;22(2):182-187. doi: 10.31486/toj.21.0065.
6
Tubulocystic Renal Cell Carcinoma Is Not an Indolent Tumor: A Case Report of Recurrences in the Retroperitoneum and Contralateral Kidney.管状囊性肾细胞癌并非惰性肿瘤:腹膜后和对侧肾脏复发的病例报告。
Medicina (Kaunas). 2021 Aug 21;57(8):851. doi: 10.3390/medicina57080851.
7
A unique presentation of a rare renal cancer: Appearance of bone metaplasia in tubulocystic renal cell carcinoma.一种罕见肾癌的独特表现:管状囊性肾细胞癌中出现骨化生。
Urol Case Rep. 2021 Jul 3;39:101767. doi: 10.1016/j.eucr.2021.101767. eCollection 2021 Nov.
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Tubulocystic renal cell carcinoma: Two-case report and literature review.管状囊性肾细胞癌:两例报告及文献复习。
Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211002966. doi: 10.1177/20587384211002966.
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Tubulocystic Renal Cell Carcinoma in Young Adult.青年成人的管状囊性肾细胞癌
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