Smolev Emma, Cohen Dorian, Mehta Nishank, Ling Kenny, Konnayil Becka, Muhlrad Samantha, Wang Edward D
Department of Orthopaedics and Rehabilitation, Stony Brook University, Stony Brook, NY, 11794-8181, USA.
Eur J Orthop Surg Traumatol. 2025 Apr 2;35(1):143. doi: 10.1007/s00590-025-04214-7.
The primary objective of this study was to investigate the association between preoperative hypertension and postoperative complications following open reduction internal fixation of distal radius fractures.
All patients who underwent open reduction internal fixation (ORIF) for distal radius fractures (DRF) between 2015 and 2021 were queried from the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database. Postoperative complications were reported within 30 days of procedure. We identified a total of 26,138 patients, and 31.5% (n = 8,225) of patients had hypertension. Hypertension was defined as blood pressure greater than 140/90 as documented in the medical record, requiring the use of an antihypertensive medication within 30 days of the operation. Multivariate logistic regression adjusted for all significantly associated variables was used to identify postoperative complications associated with preoperative systemic hypertension.
Characteristics of patients significantly associated with systemic hypertension were age ≥ 65 (p < 0.001), female gender (p < 0.001), body mass index (BMI) ≥ 30 (p < 0.001), American Society of Anesthesiologist (ASA) ≥ 3 (p < 0.001), dependent functional status (p < 0.001), smoking (p < 0.001), non-insulin-dependent diabetes (p < 0.001), chronic obstructive pulmonary disease (p < 0.001), congestive heart failure (p < 0.001), chronic steroid use (p < 0.001), and bleeding disorder (p < 0.001). After controlling for significantly associated variables, postoperative complications significantly associated with systemic hypertensive status were major complication (OR 1.83, 95% CI 1.10-3.05; p = 0.020), urinary tract infection (OR 2.02, 95% CI 1.04-3.90; p = 0.037), and non-home discharge (OR 3.48, 95% CI 2.95-4.10; p < 0.001).
Preoperative hypertension requiring medication is an independent predictor for major complication, urinary tract infection, and non-home discharge following ORIF for distal radius fractures. A better understanding of preoperative risk factors, such as a patient's hypertensive status, may aid physicians to identify patients at increased risk for postoperative complications and to better counsel patients prior to management of DRF.
本研究的主要目的是调查桡骨远端骨折切开复位内固定术后并发症与术前高血压之间的关联。
从美国外科医师学会国家外科质量改进计划(NSQIP)数据库中查询2015年至2021年间接受桡骨远端骨折(DRF)切开复位内固定(ORIF)的所有患者。术后并发症在术后30天内报告。我们共确定了26138例患者,其中31.5%(n = 8225)的患者患有高血压。高血压定义为病历中记录的血压大于140/90,且在手术30天内需要使用抗高血压药物。使用对所有显著相关变量进行调整的多因素逻辑回归来确定与术前系统性高血压相关的术后并发症。
与系统性高血压显著相关的患者特征包括年龄≥65岁(p < 0.001)、女性(p < 0.001)、体重指数(BMI)≥30(p < 0.001)、美国麻醉医师协会(ASA)分级≥3(p < 0.001)、依赖性功能状态(p < 0.001)、吸烟(p < 0.001)、非胰岛素依赖型糖尿病(p < 0.001)、慢性阻塞性肺疾病(p < 0.001)、充血性心力衰竭(p < 0.001)、长期使用类固醇(p < 0.001)和出血性疾病(p < 0.001)。在控制了显著相关变量后,与系统性高血压状态显著相关的术后并发症包括主要并发症(比值比[OR]1.83,95%置信区间[CI]1.10 - 3.05;p = 0.020)、尿路感染(OR 2.02,95% CI 1.04 - 3.90;p = 0.037)和非回家出院(OR 3.48,95% CI 2.95 - 4.10;p < 0.001)。
需要药物治疗的术前高血压是桡骨远端骨折切开复位内固定术后主要并发症、尿路感染和非回家出院的独立预测因素。更好地了解术前风险因素,如患者的高血压状态,可能有助于医生识别术后并发症风险增加的患者,并在桡骨远端骨折治疗前更好地为患者提供咨询。