单一酶变成了一把多功能军刀。
A single enzyme becomes a Swiss Army knife.
作者信息
Sichert Andreas
机构信息
Institute of Molecular Systems Biology, ETH Zürich, Zurich, Switzerland.
出版信息
PLoS Biol. 2025 Apr 2;23(4):e3003072. doi: 10.1371/journal.pbio.3003072. eCollection 2025 Apr.
Abstract
An alga that abandoned photosynthesis? This Primer explores a PLOS Biology study showing that a single horizontal gene transfer event allowed the diatom Nitzschia sing1 to evolve a complete enzymatic machinery to break down alginate from brown algae, unlocking a new ecological niche.
摘要
一种放弃光合作用的藻类？本入门文章探讨了一项发表于《公共科学图书馆·生物学》的研究，该研究表明，一次水平基因转移事件使硅藻Nitzschia sing1进化出一套完整的酶机制，用于分解褐藻中的藻酸盐，从而开拓了一个新的生态位。
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本文引用的文献
1
Diatom heterotrophy on brown algal polysaccharides emerged through horizontal gene transfer, gene duplication, and neofunctionalization.硅藻对褐藻多糖的异养作用是通过水平基因转移、基因复制和新功能化产生的。
PLoS Biol. 2025 Apr 1;23(4):e3003038. doi: 10.1371/journal.pbio.3003038. eCollection 2025 Apr.
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Secreted pectin monooxygenases drive plant infection by pathogenic oomycetes.分泌果胶单加氧酶驱动植物被致病卵菌感染。
Science. 2021 Aug 13;373(6556):774-779. doi: 10.1126/science.abj1342.
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The Biogeochemistry of Marine Polysaccharides: Sources, Inventories, and Bacterial Drivers of the Carbohydrate Cycle.海洋多糖的生物地球化学：碳水化合物循环的来源、储量和细菌驱动因素。
Ann Rev Mar Sci. 2021 Jan;13:81-108. doi: 10.1146/annurev-marine-032020-012810. Epub 2020 Jul 29.
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Adaptive radiation by waves of gene transfer leads to fine-scale resource partitioning in marine microbes.基因转移浪潮引发的适应性辐射导致海洋微生物在小尺度上进行资源分配。
Nat Commun. 2016 Sep 22;7:12860. doi: 10.1038/ncomms12860.
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Microbial interactions lead to rapid micro-scale successions on model marine particles.微生物相互作用导致模型海洋颗粒上的快速微观演替。
Nat Commun. 2016 Jun 17;7:11965. doi: 10.1038/ncomms11965.
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An engineered microbial platform for direct biofuel production from brown macroalgae.一种用于从褐藻直接生产生物燃料的工程化微生物平台。
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