Yap Adrian Ujin, Kim Sunghae, Jo Jung Hwan, Lee Byeong-Min, Park Ji Woon
Department of Dentistry, Ng Teng Fong General Hospital and Faculty of Dentistry, National University Health System, Singapore; National Dental Research Institute Singapore, National Dental Centre Singapore and Duke-NUS Medical School, Singapore Health Services, Singapore.
Dental Research Institute, Seoul National University, Seoul, South Korea; Center for Future Dentistry, Seoul National University School of Dentistry, Seoul, South Korea.
Int Dent J. 2025 Jun;75(3):1713-1721. doi: 10.1016/j.identj.2025.03.010. Epub 2025 Apr 1.
This cross-sectional study investigated the prevalence/severity of somatic symptoms, their relationship with psychological distress and oral behaviors in different temporomandibular disorder (TMD) diagnostic subtypes, and identified biopsychosocial factors associated with depression, anxiety, and jaw overuse behavior among East Asian patients.
Anonymized data from consecutive new TMD patients at a tertiary oral medicine clinic were evaluated. TMD diagnoses were determined using the DC/TMD methodology, while somatic symptoms, depression, anxiety, and oral behaviors were assessed with the Patient Health Questionnaire (PHQ)-15, PHQ-9, Generalized Anxiety Disorder Scale-7, and Oral Behavior Checklist. Data were examined using the Chi-square/non-parametric tests and multivariate linear regression analysis (α = 0.05).
Among the 699 patients, somatic symptoms were present in 36.8%, 54.0%, and 48.2% of individuals with intra-articular (IT), pain-related (PT), and combined (CT) TMDs respectively. Significant differences in somatic symptom burden/depression (PT, CT > IT) and anxiety (CT > IT) were observed. For all TMD subtypes, patients with somatic symptoms showed significantly greater depression, anxiety, and jaw overuse behavior compared to those without somatic symptoms. Somatic symptoms were moderately correlated with depression and anxiety (r = 0.51-0.65).
Somatic symptom burden was linked to depression and anxiety, supporting the phenomenon of somatization across different TMD subtypes.
本横断面研究调查了不同颞下颌关节紊乱病(TMD)诊断亚型中躯体症状的患病率/严重程度、它们与心理困扰及口腔行为的关系,并确定了东亚患者中与抑郁、焦虑和下颌过度使用行为相关的生物心理社会因素。
对一家三级口腔医学诊所连续就诊的新TMD患者的匿名数据进行评估。使用DC/TMD方法确定TMD诊断,同时用患者健康问卷(PHQ)-15、PHQ-9、广泛性焦虑障碍量表-7和口腔行为检查表评估躯体症状、抑郁、焦虑和口腔行为。使用卡方检验/非参数检验和多元线性回归分析(α = 0.05)对数据进行检验。
在699例患者中,关节内紊乱(IT)型、疼痛相关(PT)型和混合型(CT)TMD患者中分别有36.8%、54.0%和48.2%存在躯体症状。观察到躯体症状负担/抑郁(PT、CT型>IT型)和焦虑(CT型>IT型)存在显著差异。对于所有TMD亚型,有躯体症状的患者与无躯体症状的患者相比,抑郁、焦虑和下颌过度使用行为更显著。躯体症状与抑郁和焦虑呈中度相关(r = 0.51 - 0.65)。
躯体症状负担与抑郁和焦虑相关,支持了不同TMD亚型中的躯体化现象。