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用平衡盐溶液进行视网膜中央动脉插管治疗视网膜动脉阻塞。

Central retinal artery catheterization for retinal artery occlusion with balanced salt solution.

作者信息

Luo Xiangdong, Wang Xiaoying, Li Yang, Chen Xiaoyan, Wang Bin, Hu Qinrui, Li Xiaoxin

机构信息

School of Medicine, Eye Institute and Affiliated Xiamen Eye Center of Xiamen University, Xiamen University, Xiamen, China.

Fujian Provincial Key Laboratory of Corneal & Ocular Surface Diseases, Xiamen, Fujian, China.

出版信息

Sci Rep. 2025 Apr 2;15(1):11210. doi: 10.1038/s41598-025-95238-w.

DOI:10.1038/s41598-025-95238-w
PMID:40175489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11965380/
Abstract

To assess the efficacy and safety of vitrectomy combined with central retinal artery Cannulation in the treatment of retinal artery occlusion. Retrospective case analysis was conducted from April 2020 to March 2022 at the Xiamen Eye Center of Xiamen University, for patients diagnosed with central retinal artery occlusion or branch retinal artery obstruction, who underwent retinal artery Cannulation within 72 h of onset. All patients underwent pre- and postoperative visual acuity, intraocular pressure, fundus photography, optical coherence tomography, wide-angle fluorescein angiography, and visual field examination. Nine patients (6 males and 3 females) with an average age of 46 ± 28.6 years (range: 16-77 years) were included. Seven eyes were diagnosed with central retinal artery occlusion, and two eyes with branch retinal artery occlusion. The average time from onset to surgery was 40.1 h. One month after treatment, logMAR visual acuity improved in all 9 eyes of 9 patients, with a statistically significant difference (P = 0.012). Fluorescein angiography showed that postoperative arm-retinal circulation time was shortened in 5 cases (5/9, 55%) and unchanged in 4 cases (4/9, 45%). After surgery, patients generally report an improvement in vision, as well as an enhancement in their field of vision. Retinal artery Cannulation can effectively improve visual acuity and visual field, shorten the arm-retinal circulation time, and promote the recovery of retinal circulation.

摘要

评估玻璃体切除术联合视网膜中央动脉插管术治疗视网膜动脉阻塞的疗效和安全性。2020年4月至2022年3月在厦门大学附属厦门眼科中心进行回顾性病例分析,纳入发病72小时内接受视网膜动脉插管术的视网膜中央动脉阻塞或视网膜分支动脉阻塞患者。所有患者均接受术前和术后视力、眼压、眼底照相、光学相干断层扫描、广角荧光素血管造影和视野检查。纳入9例患者(男6例,女3例),平均年龄46±28.6岁(范围:16 - 77岁)。其中7只眼诊断为视网膜中央动脉阻塞,2只眼为视网膜分支动脉阻塞。从发病到手术的平均时间为40.1小时。治疗1个月后,9例患者的9只眼logMAR视力均有改善,差异有统计学意义(P = 0.012)。荧光素血管造影显示,术后5例(5/9,55%)臂 - 视网膜循环时间缩短,4例(4/9,45%)无变化。术后患者普遍反映视力改善,视野也有所扩大。视网膜动脉插管术可有效提高视力和视野,缩短臂 - 视网膜循环时间,促进视网膜循环恢复。

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本文引用的文献

1
Application of Subretinal Balanced Salt Solution Injection: A Novel technique in treating Severe idiopathic Epiretinal Membrane.视网膜下平衡盐溶液注射的应用:一种治疗严重特发性视网膜前膜的新技术。
Retina. 2024 Oct 3. doi: 10.1097/IAE.0000000000004282.
2
A Review of Current Literature on Central Retinal Artery Occlusion: Its Pathogenesis, Clinical Management, and Treatment.视网膜中央动脉阻塞的当前文献综述:其发病机制、临床管理与治疗
Cureus. 2024 Mar 8;16(3):e55814. doi: 10.7759/cureus.55814. eCollection 2024 Mar.
3
Central retinal artery occlusion: a stroke of the eye.
视网膜中央动脉阻塞:眼中风。
Eye (Lond). 2024 Aug;38(12):2319-2326. doi: 10.1038/s41433-024-03029-w. Epub 2024 Mar 28.
4
Retinal arterial and vein occlusion: is surgery ever indicated?视网膜动脉和静脉阻塞:手术是否有指正?
Curr Opin Ophthalmol. 2024 May 1;35(3):210-216. doi: 10.1097/ICU.0000000000001045. Epub 2024 Feb 28.
5
Progress in central retinal artery occlusion: a narrative review.视网膜中央动脉阻塞的研究进展:一篇综述。
J Int Med Res. 2023 Sep;51(9):3000605231198388. doi: 10.1177/03000605231198388.
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Management of Central Retinal Artery Occlusion: A Scientific Statement From the American Heart Association.《中央视网膜动脉阻塞管理:美国心脏协会的科学声明》。
Stroke. 2021 Jun;52(6):e282-e294. doi: 10.1161/STR.0000000000000366. Epub 2021 Mar 8.
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The actual role of thrombolytic treatment in central retinal artery occlusion.视网膜中央动脉阻塞的溶栓治疗的实际作用。
Arch Soc Esp Oftalmol (Engl Ed). 2021 May;96(5):231-235. doi: 10.1016/j.oftal.2020.09.016. Epub 2021 Jan 2.
8
[Intra-retinal vein cannulation without tissue-type plasminogen activator for hemi-central retinal artery occlusion].[不使用组织型纤溶酶原激活剂进行视网膜内静脉插管治疗半侧视网膜中央动脉阻塞]
Zhonghua Yan Ke Za Zhi. 2020 Jul 11;56(7):536-538. doi: 10.3760/cma.j.cn112142-20200317-00194.
9
Treatment of Nonarteritic Acute Central Retinal Artery Occlusion.非动脉炎性急性中央视网膜动脉阻塞的治疗。
Asia Pac J Ophthalmol (Phila). 2018 Jul-Aug;7(4):235-241. doi: 10.22608/APO.201871. Epub 2018 May 2.
10
Intra-Arterial Thrombolysis for Acute Central Retinal Artery Occlusion: A Systematic Review and Meta-Analysis.急性视网膜中央动脉阻塞的动脉内溶栓治疗:系统评价与Meta分析
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