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肥胖与低收入和中等收入国家的抑郁症有关吗?来自印度尼西亚的纵向证据。

Is obesity associated with depression in low- and middle-income countries? Longitudinal evidence from Indonesia.

作者信息

Colozza David, Guo Isabella, Padmita Astrid Citra, Arihandayani Yunita, Firna Evi, Avendano Mauricio

机构信息

Nutrition Section, UNICEF, Jakarta, Indonesia.

Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

出版信息

Int J Obes (Lond). 2025 Apr 3. doi: 10.1038/s41366-025-01757-x.

Abstract

BACKGROUND

In high-income countries, higher body weight is associated with increased risk of depressive symptoms. However, it is unclear whether this relationship applies to low-and-middle-income countries at earlier stages of the epidemiological transition. This study uses longitudinal data to examine the relationship between body weight and depressive symptoms in Indonesia.

METHODS

The study employs a longitudinal sample of adolescents aged 14-19 (N = 3360) and adults aged ≥20 (N = 25,669) derived from the 2007 and 2015 Indonesia Family Life Survey. Depressive symptoms were assessed using the Centre for Epidemiologic Studies Depression ten-item scale (CES-D-10). Anthropometric measurements taken by trained nurses were used to calculate overweight/obesity (BMI ≥ 23), our outcome of interest. We use linear random and individual fixed effect models, stratified by gender and age group.

RESULTS

In random effects models, there was no association between overweight and depressive symptoms among adolescents, while overweight was associated with lower depressive symptoms among adults. These results were confirmed in fixed effect models: there was no association for adolescents (-0.32, 95% Confidence Interval [CI] -0.84, 0.21), while among adults, becoming overweight was associated with a significant reduction in depressive symptoms (-0.25, 95% CI -0.43, -0.08). There was no evidence of significant differences by sex.

CONCLUSIONS

Contrary to high-income countries, we found no evidence of an association between depressive symptoms and overweight among adolescents in Indonesia, while depressive symptoms are associated with reduced risk of overweight among adults. Findings may be due to lower overweight stigma in Indonesia's socio-cultural environment, potential depressive symptom underestimation, and a moderating role of socioeconomic status. Given the rising overweight burden in Indonesia, our results highlight the need to prioritise policies addressing structural causes rather than individual factors, in order to avoid promoting overweight stigma and safeguard mental health.

摘要

背景

在高收入国家,较高的体重与抑郁症状风险增加相关。然而,尚不清楚这种关系是否适用于处于流行病学转变早期阶段的低收入和中等收入国家。本研究使用纵向数据来检验印度尼西亚体重与抑郁症状之间的关系。

方法

该研究采用了来自2007年和2015年印度尼西亚家庭生活调查的纵向样本,包括14 - 19岁的青少年(N = 3360)和20岁及以上的成年人(N = 25669)。使用流行病学研究中心抑郁十项量表(CES - D - 10)评估抑郁症状。由训练有素的护士进行人体测量,以计算超重/肥胖(BMI≥23),这是我们感兴趣的结果。我们使用线性随机和个体固定效应模型,按性别和年龄组进行分层。

结果

在随机效应模型中,青少年中超重与抑郁症状之间没有关联,而成年人中超重与较低的抑郁症状相关。这些结果在固定效应模型中得到证实:青少年中无关联(-0.32,95%置信区间[CI] -0.84,0.21),而在成年人中,超重与抑郁症状显著减轻相关(-0.25,95% CI -0.43,-0.08)。没有证据表明存在性别差异。

结论

与高收入国家相反,我们没有发现印度尼西亚青少年中抑郁症状与超重之间存在关联的证据,而成年人中抑郁症状与超重风险降低相关。研究结果可能归因于印度尼西亚社会文化环境中较低的超重污名、潜在的抑郁症状低估以及社会经济地位的调节作用。鉴于印度尼西亚超重负担不断上升,我们的结果强调需要优先制定解决结构性原因而非个体因素的政策,以避免加剧超重污名并保障心理健康。

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