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改良颈部引流在食管癌患者颈部吻合口瘘管理中的应用

Application of modified neck drainage in the management of cervical anastomotic fistula in esophageal cancer patients.

作者信息

Wu Song, Zhang Zhe, Qin Zhonghua

机构信息

Department of Thoracic Surgery, Jiangyin People's Hospital, 3 Yingrui Road, Jiangyin, Jiangsu Province, 214400, China.

出版信息

J Cardiothorac Surg. 2025 Apr 2;20(1):173. doi: 10.1186/s13019-025-03401-1.

DOI:10.1186/s13019-025-03401-1
PMID:40176143
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11963416/
Abstract

BACKGROUND

Anastomotic fistula is a rare but life-threatening complication of esophageal cancer, and its treatment remains challenging.We aimed to evaluate the clinical efficacy of modified cervical drainage in the management of cervical anastomotic fistula in patients after esophageal cancer surgery.

METHODS

From June 2017 to December 2021, 25 esophageal cancer patients who developed cervical anastomotic fistula were enrolled in the study. Among them, 14 patients were treated with modified cervical drainage, which served as the observation group, while the remaining 11 patients underwent open incision and drainage, which served as the control group. The treatment outcomes of the two groups were compared and analyzed.

RESULTS

The observation group had a significantly shorter healing time, fewer dressing changes, shorter hospital stay, and lower hospitalization costs compared to the control group (P < 0.05). The incidence of complications in the neck was not significantly different between the two groups (P > 0.05). All patients resumed a normal diet without experiencing fever, coughing or other discomfort, and were discharged after a smooth recovery.

CONCLUSIONS

Modified neck drainage, as a treatment method for cervical anastomotic leakage in esophageal cancer patients, has preliminarily demonstrated potential in promoting patient recovery. However, its efficacy still requires further validation and confirmation through studies with larger sample sizes.

摘要

背景

吻合口瘘是食管癌一种罕见但危及生命的并发症,其治疗仍然具有挑战性。我们旨在评估改良颈部引流术在食管癌手术后患者颈部吻合口瘘管理中的临床疗效。

方法

2017年6月至2021年12月,25例发生颈部吻合口瘘的食管癌患者纳入本研究。其中,14例患者采用改良颈部引流术治疗,作为观察组,其余11例患者行开放切开引流术,作为对照组。比较分析两组的治疗效果。

结果

与对照组相比,观察组愈合时间明显缩短,换药次数减少,住院时间缩短,住院费用降低(P<0.05)。两组颈部并发症发生率差异无统计学意义(P>0.05)。所有患者均恢复正常饮食,未出现发热、咳嗽或其他不适,康复顺利后出院。

结论

改良颈部引流术作为食管癌患者颈部吻合口漏的一种治疗方法,在促进患者康复方面初步显示出潜力。然而,其疗效仍需通过更大样本量的研究进一步验证和确认。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1019/11963416/a510f76abe0b/13019_2025_3401_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1019/11963416/a510f76abe0b/13019_2025_3401_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1019/11963416/a510f76abe0b/13019_2025_3401_Fig1_HTML.jpg

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本文引用的文献

1
[Epidemiological characteristic and current status of surgical treatment for esophageal cancer by analysis of national registry database].通过国家登记数据库分析食管癌外科治疗的流行病学特征及现状
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Cardiorespiratory Comorbidity and Postoperative Complications following Esophagectomy: a European Multicenter Cohort Study.心肺合并症与食管癌术后并发症:一项欧洲多中心队列研究。
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Minimally invasive McKeown's vs open oesophagectomy for cancer: A meta-analysis.
微创 McKeown 手术与开放性食管癌切除术治疗癌症的比较:一项荟萃分析。
Eur J Surg Oncol. 2019 Jun;45(6):941-949. doi: 10.1016/j.ejso.2018.11.017. Epub 2018 Nov 24.
4
Updated experiences with minimally invasive McKeown esophagectomy for esophageal cancer.微创McKeown食管癌切除术的最新经验
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