Hasan Mohammad Jahid, Islam Muna, Tabassum Tanjina, Khan Md Mohiuddin, Islam Md Khairul, Afroz Rafiya, Tui Rubaiya Rahman, Baset Mohammad Abdul, Syed Md Anwar, Manzoor Joarder Rakeen, Sharif Mohiuddin, Tabassum Tamanna
Tropical Disease and Health Research Center, Dhaka, 1100, Bangladesh.
Department of Medicine, Chittagong Medical College Hospital, Chittagong, 4203, Bangladesh.
Trop Med Health. 2025 Apr 2;53(1):45. doi: 10.1186/s41182-025-00691-y.
Dengue fever remains a significant public health challenge in Bangladesh. This study aimed to characterize the clinical and epidemiological profiles of confirmed dengue cases during the 2024 outbreak in Bangladesh.
This observational study was conducted from June to September 2024 in four tertiary care hospitals across Bangladesh located in four administrative divisions. A total of 401 laboratory-confirmed (NS1- or IgM-positive) dengue patients aged ≥ 12 years were included. Demographic data, clinical presentations, and laboratory findings were collected through face‒to-face interviews. The revised WHO 2009 dengue case classification was used for severity assessment of dengue patients. Descriptive and inferential statistics were used to summarize the results.
The mean age of patients with dengue fever was 29.81 ± 11.64 (SD) years, with 7.2% of the patients being adolescents (aged 12-17 years). A clear male predominance (88.3%) was observed. Overall, 65.6% of patients had dengue with warning signs, and 9% had severe dengue. Fever (94.3%), headache (70.3%), myalgia (66.1%), and gastrointestinal symptoms such as nausea (49.9%) and abdominal pain (43.9%) were common symptoms. The median in-hospital stay of both non-severe and severe cases were 4 & 5 days, respectively. The in-hospital mortality rate was 0.75%, which was significantly higher among severe dengue patients (5.6%).
The 2024 dengue outbreak in Bangladesh predominantly affected young adult males, with a notable prevalence of gastrointestinal symptoms alongside classic dengue manifestations.
登革热仍是孟加拉国一项重大的公共卫生挑战。本研究旨在描述孟加拉国2024年登革热疫情期间确诊登革热病例的临床和流行病学特征。
本观察性研究于2024年6月至9月在孟加拉国四个行政区的四家三级护理医院进行。纳入了401例年龄≥12岁的实验室确诊（NS1或IgM阳性）登革热患者。通过面对面访谈收集人口统计学数据、临床表现和实验室检查结果。采用2009年修订的世界卫生组织登革热病例分类法对登革热患者进行严重程度评估。使用描述性和推断性统计方法总结结果。
登革热患者的平均年龄为29.81±11.64（标准差）岁，其中7.2%为青少年（12 - 17岁）。观察到明显的男性优势（88.3%）。总体而言，65.6%的患者有登革热且伴有警示体征，9%的患者患有重症登革热。发热（94.3%）、头痛（70.3%）、肌痛（66.1%）以及恶心（49.9%）和腹痛（43.9%）等胃肠道症状是常见症状。非重症和重症病例的中位住院时间分别为4天和5天。住院死亡率为0.75%，在重症登革热患者中显著更高（5.6%）。
2024年孟加拉国的登革热疫情主要影响年轻成年男性，除了典型的登革热表现外，胃肠道症状也较为普遍。
