Ferreira H C M, Ferreira R R F, Pinto S C P, Mesa-Sanchez I
Animal Blood Bank, Porto, Portugal.
Animal Blood Bank, Barcelona, Spain.
J Small Anim Pract. 2025 Aug;66(8):556-560. doi: 10.1111/jsap.13861. Epub 2025 Apr 2.
This article aims to analyse the safety of canine blood donation by describing the frequency and causes of any adverse reactions in donors.
In this prospective study, any blood donor adverse reactions detected by the clinical staff during and immediately after donation were recorded. The owners of the dogs were also surveyed by a veterinary practitioner or veterinary nurse 3 days after donation, using a predefined questionnaire to assess for any clinical or behavioural changes. Data were collected between December 2020 and December 2021 from blood donors enrolled in an animal blood bank programme.
From the 4439 blood donations, 37 (0.83%) adverse post-donation reactions were reported, with no other reactions identified in the remaining 4402 donations (99.17%). Of the total of donations in the studied period, 0.63% (n = 28) of canine donors developed a haematoma in the puncture area, 0.11% (n = 5) developed mild bleeding at the puncture site during the monitoring period, 0.045% (n = 2) developed a skin rash after clipping for donation, and 0.045% (n = 2) developed acute weakness, pallor, tachycardia and tachypnoea during the 30 minutes monitoring period, consistent with hypotension. In both cases showing acute signs of weakness, pallor, tachycardia and tachypnoea, all parameters stabilised and resolved within 10 to 15 minutes upon administration of a 10 mL/kg bolus over 10 minutes of intravenous NaCl. No other delayed reactions were reported by the owners other than the acute reactions already registered by the donation staff.
The low incidence of post-donation reactions in this study is encouraging, suggesting that a high level of safety can be achieved in a structured canine blood donation programme.
本文旨在通过描述献血犬的不良反应发生频率及原因，分析犬献血的安全性。
在这项前瞻性研究中，记录临床工作人员在献血期间及献血后立即检测到的任何献血犬不良反应。献血犬的主人还在献血3天后接受兽医或兽医护士的调查，使用预先定义的问卷评估是否有任何临床或行为变化。2020年12月至2021年12月期间，从参加动物血库项目的献血犬中收集数据。
在4439次献血中，报告了37次（0.83%）献血后不良反应，其余4402次献血（99.17%）未发现其他反应。在研究期间的所有献血中，0.63%（n = 28）的献血犬在穿刺部位出现血肿，0.11%（n = 5）在监测期内在穿刺部位出现轻度出血，0.045%（n = 2）在剪毛献血后出现皮疹，0.045%（n = 2）在30分钟监测期内出现急性虚弱、苍白、心动过速和呼吸急促，符合低血压表现。在出现急性虚弱、苍白、心动过速和呼吸急促症状的两例中，静脉注射10 mL/kg的生理盐水，在10分钟内推注完毕，所有参数在10至15分钟内稳定并恢复正常。除了献血工作人员已经记录的急性反应外，主人未报告其他延迟反应。
本研究中献血后反应的低发生率令人鼓舞，表明在结构化的犬献血项目中可以实现较高的安全性。
