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增强淋巴瘤分期:揭示全身磁共振成像的潜力与挑战

Enhancing lymphoma staging: Unveiling the potential and challenges of whole-body magnetic resonance imaging.

作者信息

Ahmadzade Mohadese, Ghasemi-Rad Mohammad

机构信息

Department of Radiology, Baylor College of Medicine, Houston, TX 77030, United States.

Department of Radiology, Section of Interventional Radiology, Baylor College of Medicine, Houston, TX 77030, United States.

出版信息

World J Radiol. 2025 Mar 28;17(3):104917. doi: 10.4329/wjr.v17.i3.104917.

DOI:10.4329/wjr.v17.i3.104917
PMID:40176957
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11959623/
Abstract

In this editorial, we comment on the article by Lambert , published in the recent issue of the . The focus of the editorial is to explore the advancements in whole-body magnetic resonance imaging (WB-MRI) technology, its current clinical applications, and the challenges that must be addressed to fully realize its potential in oncological imaging. WB-MRI has emerged as a pivotal tool in oncological imaging, offering comprehensive disease assessment without ionizing radiation. Its applications span the detection of bone metastases, evaluation of hematologic malignancies, and staging of a wide range of cancers, including lymphoma, prostate, and breast cancers. Advanced techniques such as diffusion-weighted imaging have enhanced its diagnostic performance by providing superior lesion-to-background contrast and quantitative metrics. Despite its diagnostic strengths, WB-MRI faces challenges in standardization, patient acceptance, and integration into clinical workflows. Variability in acquisition protocols, hardware differences, and patient-related factors, such as anxiety and motion artifacts, have limited widespread adoption. Emerging guidelines like MET-RADS-P and ONCO-RADS aim to address these issues by promoting standardized protocols tailored to specific clinical needs. This editorial explores the advancements in WB-MRI technology, its current clinical applications, and the barriers that must be overcome to maximize its utility. By addressing these challenges and embracing standardization, WB-MRI holds the potential to redefine the landscape of oncological imaging, aligning diagnostic precision with modern treatment goals of reducing long-term patient risk.

摘要

在这篇社论中,我们对兰伯特发表于最近一期[期刊名称未给出]上的文章进行评论。社论的重点是探讨全身磁共振成像(WB-MRI)技术的进展、其当前的临床应用,以及要充分发挥其在肿瘤成像方面的潜力必须解决的挑战。WB-MRI已成为肿瘤成像中的关键工具,可在不使用电离辐射的情况下提供全面的疾病评估。其应用涵盖骨转移的检测、血液系统恶性肿瘤的评估以及多种癌症的分期,包括淋巴瘤、前列腺癌和乳腺癌。诸如扩散加权成像等先进技术通过提供卓越的病变与背景对比度及定量指标,提升了其诊断性能。尽管具有诊断优势,但WB-MRI在标准化、患者接受度以及融入临床工作流程方面面临挑战。采集协议的差异、硬件不同以及患者相关因素,如焦虑和运动伪影,限制了其广泛应用。像MET-RADS-P和ONCO-RADS这样的新兴指南旨在通过推广针对特定临床需求的标准化协议来解决这些问题。这篇社论探讨了WB-MRI技术的进展、其当前的临床应用以及为最大化其效用必须克服的障碍。通过应对这些挑战并采用标准化,WB-MRI有潜力重新定义肿瘤成像的格局,使诊断精度与降低患者长期风险的现代治疗目标相一致。

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本文引用的文献

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Whole-body magnetic resonance imaging provides accurate staging of diffuse large B-cell lymphoma, but is less preferred by patients.全身磁共振成像可为弥漫性大B细胞淋巴瘤提供准确的分期,但患者对此的接受度较低。
World J Radiol. 2025 Jan 28;17(1):99207. doi: 10.4329/wjr.v17.i1.99207.
2
Deep learning and AI in reducing magnetic resonance imaging scanning time: advantages and pitfalls in clinical practice.深度学习与人工智能在缩短磁共振成像扫描时间方面的应用:临床实践中的优势与陷阱
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Second Cancers in Classical Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma: A Systematic Review by the Fondazione Italiana Linfomi.经典型霍奇金淋巴瘤和弥漫性大B细胞淋巴瘤中的二次癌症:意大利淋巴瘤基金会的系统评价
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4
Oncologically Relevant Findings Reporting and Data System (ONCO-RADS): Guidelines for the Acquisition, Interpretation, and Reporting of Whole-Body MRI for Cancer Screening.肿瘤学相关发现报告和数据系统(ONCO-RADS):用于癌症筛查的全身 MRI 采集、解读和报告的指南。
Radiology. 2021 Jun;299(3):494-507. doi: 10.1148/radiol.2021201740. Epub 2021 Apr 27.
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Comparison of Whole-Body DWI and F-FDG PET/CT for Detecting Intramedullary and Extramedullary Lesions in Multiple Myeloma.全身弥散加权成像与 F-FDG PET/CT 检测多发性骨髓瘤髓内及髓外病变的比较。
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Assessment of response to chemotherapy in pancreatic ductal adenocarcinoma: Comparison between diffusion-weighted MR quantitative parameters and RECIST.胰腺导管腺癌化疗反应评估:扩散加权 MR 定量参数与 RECIST 比较。
Eur J Radiol. 2018 Jul;104:49-57. doi: 10.1016/j.ejrad.2018.04.024. Epub 2018 Apr 27.
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Radiology. 2015 Aug;276(2):323-38. doi: 10.1148/radiol.2015142088.
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