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1例肝门部胆管癌门静脉切除及肝切除术后急性门静脉血栓形成的血管内治疗病例。

A case of endovascular treatment for acute portal vein thrombosis following portal vein resection and hepatectomy for hilar cholangiocarcinoma.

作者信息

Oguz Sukru, Küçükaslan Hakan, Altun Gokalp, Basar Dilek, Topaloglu Serdar, Calik Adnan

机构信息

Department of Radiology, School of Medicine, Karadeniz Technical University, Trabzon 61080, Turkey.

Department of Surgery, Trabzon Akçaabat Haçkalı Baba Devlet Hastanesi, Trabzon 61080, Turkey.

出版信息

BJR Case Rep. 2025 Mar 20;11(2):uaaf017. doi: 10.1093/bjrcr/uaaf017. eCollection 2025 Mar.

DOI:10.1093/bjrcr/uaaf017
PMID:40177368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11964485/
Abstract

Currently, portal vein (PV) resection is performed in 10%-40% of liver resections performed for hilar cholangiocarcinoma (HC). The defect is generally repaired with a patch of an autologous vein graft or end-to-end anastomosis after complete separation of the main PV trunk and the left PV. Postoperative PV thrombosis is a severe complication occurring in 2%-9% of patients requiring PV reconstruction. Here in, we presented a 55-year-old man with abdominal pain without hyperbilirubinaemia who was diagnosed with HC. The patient underwent right hepatectomy, extrahepatic biliary resection, and PV resection. The PV defect was repaired with autologous umbilical vein graft. Following the operation, acute PV thrombosis was encountered postoperative day 1. We conducted the treatment of the early acute PV thrombosis by intraportal tPA and PV stenting with endovascular approach.

摘要

目前,在为肝门部胆管癌(HC)进行的肝切除术中,10% - 40%的手术会进行门静脉(PV)切除。缺损通常在主PV干和左PV完全分离后,用一块自体静脉移植物修补或进行端端吻合来修复。术后PV血栓形成是一种严重并发症,在需要PV重建的患者中发生率为2% - 9%。在此,我们报告一名55岁男性,有腹痛但无高胆红素血症,被诊断为HC。该患者接受了右半肝切除术、肝外胆管切除术和PV切除术。PV缺损用自体脐静脉移植物修复。术后第1天出现急性PV血栓形成。我们通过门静脉内注射组织型纤溶酶原激活剂(tPA)和采用血管内介入方法进行PV支架置入术对早期急性PV血栓形成进行了治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d847/11964485/ad5b5a3a1078/uaaf017f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d847/11964485/f837488bdfbf/uaaf017f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d847/11964485/ad5b5a3a1078/uaaf017f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d847/11964485/f837488bdfbf/uaaf017f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d847/11964485/ad5b5a3a1078/uaaf017f2.jpg

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本文引用的文献

1
Combined Vascular Resection for Locally Advanced Perihilar Cholangiocarcinoma.联合血管切除治疗局部进展期肝门部胆管癌
Ann Surg. 2022 Feb 1;275(2):382-390. doi: 10.1097/SLA.0000000000004322.
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Posthepatectomy liver failure.肝切除术后肝衰竭。
Turk J Med Sci. 2020 Oct 22;50(6):1491-1503. doi: 10.3906/sag-2006-31.
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Enhancing Hepatic Microcirculation in Postoperative Hepatic Failure With Intra-arterial Recombinant Tissue Plasminogen Activator Treatment.动脉内注射重组组织型纤溶酶原激活剂治疗对术后肝衰竭肝微循环的改善作用
Exp Clin Transplant. 2017 Dec 18. doi: 10.6002/ect.2017.0074.
4
Combined portal vein resection for hilar cholangiocarcinoma: a meta-analysis of comparative studies.联合门静脉切除治疗肝门部胆管癌:荟萃分析比较研究。
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5
Evolution of surgical treatment for perihilar cholangiocarcinoma: a single-center 34-year review of 574 consecutive resections.肝门部胆管癌外科治疗的演变:单中心 34 年 574 例连续切除术回顾。
Ann Surg. 2013 Jul;258(1):129-40. doi: 10.1097/SLA.0b013e3182708b57.
6
Posthepatectomy liver failure: a definition and grading by the International Study Group of Liver Surgery (ISGLS).术后肝衰竭:国际肝脏外科研究组织(ISGLS)的定义和分级。
Surgery. 2011 May;149(5):713-24. doi: 10.1016/j.surg.2010.10.001. Epub 2011 Jan 14.
7
Risk factors for liver failure and mortality after hepatectomy associated with portal vein resection.与门静脉切除相关的肝切除术后肝功能衰竭和死亡率的危险因素。
Ann Surg. 2011 Jan;253(1):173-9. doi: 10.1097/SLA.0b013e3181f193ba.
8
Transcatheter thrombolytic therapy for acute mesenteric and portal vein thrombosis.经导管溶栓治疗急性肠系膜和门静脉血栓形成
J Vasc Interv Radiol. 2005 May;16(5):651-61. doi: 10.1097/01.RVI.0000156265.79960.86.