López-Vera Eduardo, Del Boz-González Javier, Castro-Ruiz Julia, Ruiz-Delgado Francisco
Hospital Regional Universitario de Málaga, Málaga, Spain.
Minidens Dental Clinic, Jerez de la Frontera, Cádiz, Spain.
Pediatr Dermatol. 2025 Sep-Oct;42(5):1066-1070. doi: 10.1111/pde.15938. Epub 2025 Apr 3.
The dental developmental abnormalities observed in two pediatric patients with segmental infantile hemangiomas (IH) not associated with PHACES syndrome (posterior fossa malformations, hemangiomas, arterial anomalies, cardiac defects, eye abnormalities, sternal cleft, and supraumbilical raphe) are presented. Both patients, treated with oral propranolol, exhibited significant dental complications, including delayed tooth eruption, enamel hypoplasia, and complete tooth agenesis. The findings suggest a potential link between facial segmental IH and dental anomalies that may be underrecognized, particularly in non-PHACES cases. We recommend considering targeted dental screenings and radiographic imaging for patients with segmental IH in high-risk facial regions, particularly those involving the maxillary and mandibular regions, to facilitate early identification and management of potential complications.
