Aujayeb Avinash, Astoul Philippe, Londero Francesco, Zuin Andrea
Respiratory Department, Northumbria Health Care NHS Foundation Trust, Care of Gail Hewitt, Newcastle, NE23 6NZ, UK.
Department of Thoracic Oncology, Pleural Diseases and Interventional Pulmonology, North Hospital, Aix-Marseille University, Marseille, France.
Pulm Ther. 2025 Jun;11(2):117-127. doi: 10.1007/s41030-025-00295-1. Epub 2025 Apr 3.
Pleural mesothelioma (PM) is a rare incurable disease, predominantly linked to asbestos exposure. Not only is diagnosis difficult, but treatment choices are often limited to systemic anti-cancer treatment with chemotherapy or immunotherapy. Surgery has been employed for decades, but its application has been fiercely debated despite some randomized controlled trials such as the recent Mesothelioma and Radical Surgery 2 (MARS 2) study. We provide a commentary on this controversial topic.
胸膜间皮瘤（PM）是一种罕见的不治之症，主要与接触石棉有关。不仅诊断困难，而且治疗选择通常仅限于化疗或免疫疗法等全身性抗癌治疗。手术已经应用了几十年，但尽管有一些随机对照试验，如最近的间皮瘤与根治性手术2（MARS 2）研究，其应用仍存在激烈争议。我们对这个有争议的话题发表评论。
