Weiss R D, Pope H G, Mirin S M
Drug Alcohol Depend. 1985 May;15(1-2):69-72. doi: 10.1016/0376-8716(85)90031-6.
Research suggests that attention deficit disorder (ADD) may persist into adulthood, perhaps predisposing certain individuals to stimulant abuse. The authors describe two adults with chronic cocaine abuse and apparent residual ADD. After failing to respond to conventional treatment modalities, these patients were administered magnesium pemoline. Both displayed a sustained reduction in their cocaine use, without abusing pemoline. This finding suggests that the diagnostic assessment of cocaine abusers should include a search for a history of ADD. A carefully selected subgroup of this population may benefit from treatment with other stimulant medications.
研究表明，注意力缺陷障碍（ADD）可能会持续到成年期，这或许会使某些个体易患兴奋剂滥用问题。作者描述了两名患有慢性可卡因滥用且明显存在残余ADD的成年人。在对传统治疗方式无反应后，给这些患者使用了匹莫林镁盐。两人的可卡因使用量均持续减少，且未滥用匹莫林。这一发现表明，对可卡因滥用者的诊断评估应包括探寻ADD病史。该人群中经过精心挑选的亚组可能会从其他兴奋剂药物治疗中获益。
