Patchitt Joel, Garfinkel Sarah, Strawson William H, Miller Mark, Tsakiris Manos, Clark Andy, Critchley Hugo D
Sussex Centre for Consciousness Science, University of Sussex, Brighton, BN1 9QJ, UK.
Department of Clinical Neuroscience, Brighton and Sussex Medical School, University of Sussex, Brighton, BN1 9RY, UK.
Sci Rep. 2025 Apr 3;15(1):11472. doi: 10.1038/s41598-025-94971-6.
Mismatches between perceived and veridical physiological signals during false feedback (FFB) can bias emotional judgements. Paradigms using auditory FFB suggest perceived changes in heart rate (HR) increase ratings of emotional intensity irrespective of feedback type (increased or decreased HR), implicating right anterior insula as a mismatch comparator between exteroceptive and interoceptive information. However, few paradigms have examined effects of somatosensory FFB. Participants rated the emotional intensity of randomized facial expressions while they received 20 s blocks of pulsatile somatosensory stimulation at rates higher than HR, lower than HR, equivalent to HR, or no stimulation during a functional magnetic resonance neuroimaging scan. FFB exerted a bidirectional effect on reported intensity ratings of the emotional faces, increasing over the course of each 20 s stimulation block. Neuroimaging showed FFB engaging regions indicative of affective touch processing, embodiment, and reflex suppression. Contrasting higher vs. lower HR FFB revealed engagement of right insula and centres supporting socio-emotional processing. Results indicate that exposure to pulsatile somatosensory stimulation can influence emotional judgements though its progressive embodiment as a perceived interoceptive arousal state, biasing how affective salience is ascribed to external stimuli. Results are consistent with multimodal integration of priors and prediction-error signalling in shaping perceptual judgments.
在错误反馈（FFB）期间，感知到的生理信号与真实生理信号之间的不匹配会使情绪判断产生偏差。使用听觉FFB的范式表明，无论反馈类型（心率增加或降低）如何，感知到的心率（HR）变化都会提高情绪强度评分，这表明右前脑岛是外感受和内感受信息之间的不匹配比较器。然而，很少有范式研究过体感FFB的影响。在功能性磁共振神经成像扫描期间，参与者对随机面部表情的情绪强度进行评分，同时他们会接受20秒的脉动体感刺激，刺激速率高于心率、低于心率、等同于心率或无刺激。FFB对所报告的情绪面孔强度评分产生双向影响，在每个20秒的刺激块过程中评分增加。神经成像显示FFB激活了指示情感触摸处理、具身化和反射抑制的区域。对比较高与较低心率的FFB发现，右脑岛和支持社会情感处理的中枢被激活。结果表明，暴露于脉动体感刺激可以通过其逐渐具身化为一种感知到的内感受唤醒状态来影响情绪判断，从而使情感显著性归因于外部刺激的方式产生偏差。结果与先验和预测误差信号的多模态整合在塑造感知判断中的作用一致。
