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一名4岁女童的药物性中毒性表皮坏死松解症(莱尔综合征)

Drug-induced toxic epidermal necrolysis (Lyell's syndrome) in a 4-year-old girl.

作者信息

Luderschmidt C, Linderkamp O, Ring J

出版信息

Eur J Pediatr. 1985 May;144(1):91-3. doi: 10.1007/BF00491939.

Abstract

Toxic epidermal necrolysis (Lyell's syndrome) with erythematous skin lesions and bulla formation developed in a 4-year-old girl. An accurate diagnosis using the cryostat technique on the top of a bulla was available within 1 h of hospital admission. The course was unusually mild, probably because of early treatment with corticosteroids. Skin prick tests revealed salicylamide as the agent responsible for inducing the disease. The patient was advised to avoid this substance for the rest of her life.

摘要

一名4岁女孩出现了伴有红斑性皮肤损害和水疱形成的中毒性表皮坏死松解症(莱尔综合征)。在入院后1小时内,通过对水疱顶部进行冷冻切片技术获得了准确诊断。病程异常轻微,可能是因为早期使用了皮质类固醇进行治疗。皮肤点刺试验显示水杨酰胺是诱发该病的物质。建议该患者余生避免接触这种物质。

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