Autonomic modulation and skeletal muscle oxygenation with intermittent low-load blood flow restriction knee extension.

INTRODUCTION

This investigation determined if an acute bout of low-load knee extension (KE) with intermittent blood flow restriction (BFR) influenced autonomic modulation and skeletal muscle oxygenation (SmO%).

METHODS

Fourteen physically active males completed three different sessions: one-repetition maximum (1RM), KE with BFR (BFR-KE) at 20% 1RM (cuff pressure=143 ± 13 mmHg), and KE with free blood flow at 20% 1RM (Control-KE). Heart rate variability (HRV) metrics: logarithmically transformed (ln) square root of the mean differences of successive R-R intervals (lnRMSSD), high frequency power (lnHF), and low frequency power (lnLF), as well as SmO%, and rating of perceived exertion (RPE) were measured. Repeated measures analyses of variance were used to analyze HRV metrics and SmO%, while a paired -test was used to analyze RPE. A significance level of   0.05 was used for analyses.

RESULTS

From baseline to 15 min post-exercise lnRMSSD decreased in both BFR-KE and Control-KE (4.34 ± 0.43-3.75 ± 0.82 ms,  = 0.027). Thereafter, lnRMSSD (+7%), lnHF (+8%), and lnLF (+7%) increased from 15 to 30 min post-exercise in both BFR-KE and Control-KE ( < 0.05). BFR-KE reduced SmO% in the vastus lateralis compared to Control-KE (36% vs. 53%;  < 0.001). RPE was greater in BFR-KE (7.0 AU) compared to Control-KE (4.5 AU;   0.001).

CONCLUSION

Unilateral BFR exercise with individualized cuff pressure and intermittent application facilitated greater localized muscular stress and perceptual effort, but there was no influence of vascular occlusion on post-exercise autonomic modulation compared to volume-matched exercise with free blood flow.