农麦角碱的δ8双键在麦角菌合成麦角酰胺中的作用。
Role of the delta 8 double bond of agroclavine in lysergic acid amide biosynthesis by Claviceps purpurea.
作者信息
Willingale J, Manzarpour A, Mantle P G
出版信息
Experientia. 1985 Aug 15;41(8):1051-2. doi: 10.1007/BF01952138.
PMID:4018228
Abstract
Agroclavine, given to actively-growing sclerotial tissue of a strain of Claviceps purpurea which can not normally elaborate ergot alkaloids, was transformed by this tissue into lysergic acid amide with overall efficiency of approximately 40%. By contrast, festuclavine (8,9-dihydro-agroclavine) was not transformed, indicating specificity in the mechanism of lysergyl biosynthesis.
摘要
将农吉利麦角碱给予一株通常不能合成麦角生物碱的紫麦角菌的正在活跃生长的菌核组织，该组织将其转化为麦角酰胺，总效率约为40%。相比之下，雀麦角碱（8,9-二氢农吉利麦角碱）未被转化，这表明麦角酰生物合成机制具有特异性。
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本文引用的文献
1
Metabolic studies on Claviceps purpurea during parasitic development on rye.麦角菌在黑麦上寄生发育过程中的代谢研究。
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Large-scale production of clavine alkaloids by Claviceps fusiformis.梭形麦角菌大规模生产麦角棒麦角碱。
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