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脊椎动物心脏粗制膜中受磷蛋白磷酸化的比较分析。

Comparative analysis of phospholamban phosphorylation in crude membranes of vertebrate hearts.

作者信息

Will H, Küttner I, Kemsies C, Vetter R, Schubert E

出版信息

Experientia. 1985 Aug 15;41(8):1052-4. doi: 10.1007/BF01952139.

DOI:10.1007/BF01952139
PMID:4018229
Abstract

Phospholamban, a sarcoplasmic reticulum phosphoprotein, is present in the hearts of mammalian, avian, amphibian, and fish species. Phylogenetic changes are indicated by marked differences among species in cardiac phospholamban content and by the absence of Ca2+/calmodulin-dependent phospholamban phosphorylation at an early developmental stage.

摘要

受磷蛋白是一种肌浆网磷蛋白,存在于哺乳动物、鸟类、两栖动物和鱼类的心脏中。系统发育变化表现为不同物种心脏中受磷蛋白含量存在显著差异,以及在发育早期阶段不存在钙/钙调蛋白依赖性受磷蛋白磷酸化。

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1
Comparative analysis of phospholamban phosphorylation in crude membranes of vertebrate hearts.脊椎动物心脏粗制膜中受磷蛋白磷酸化的比较分析。
Experientia. 1985 Aug 15;41(8):1052-4. doi: 10.1007/BF01952139.
2
Cardiac sarcoplasmic-reticulum calmodulin-binding proteins. Modulation of calmodulin binding to phospholamban by phosphorylation.心肌肌浆网钙调蛋白结合蛋白。磷酸化对钙调蛋白与受磷蛋白结合的调节作用。
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Inhibition of endogenous cardiac phosphatase activity and measurement of sarcoplasmic reticulum calcium uptake: a possible role of phospholamban phosphorylation in the hypertrophied myocardium.内源性心脏磷酸酶活性的抑制及肌浆网钙摄取的测定:受磷蛋白磷酸化在肥厚心肌中的可能作用
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Phospholamban-mediated stimulation of Ca2+ uptake in sarcoplasmic reticulum from normal and failing hearts.磷酸受磷蛋白介导的正常及衰竭心脏肌浆网对钙离子摄取的刺激作用
J Clin Invest. 1990 May;85(5):1698-702. doi: 10.1172/JCI114623.
5
Subunit structure and multiple phosphorylation sites of phospholamban.
J Biochem. 1986 Jan;99(1):41-53. doi: 10.1093/oxfordjournals.jbchem.a135478.
6
Identification of a calmodulin-dependent protein kinase in the cardiac cytosol, which phosphorylates phospholamban in the sarcoplasmic reticulum.在心肌细胞质中鉴定出一种钙调蛋白依赖性蛋白激酶,该激酶可使肌浆网中的受磷蛋白磷酸化。
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Ca2+/calmodulin-dependent phospholamban kinase from cardiac sarcoplasmic reticulum is distinct from phosphorylase kinase and forms a regulatory complex with phospholamban and the Ca2+-ATPase.来自心肌肌浆网的钙调蛋白依赖性受磷蛋白激酶不同于磷酸化酶激酶,并与受磷蛋白和钙ATP酶形成调节复合物。
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Phospholamban, the regulator of the cardiac sarcoplasmic reticulum calcium pump, does not copurify with the Ca2+-ATPase enzyme.受磷蛋白,即心肌肌浆网钙泵的调节蛋白,不会与Ca2+-ATP酶一起共纯化。
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Catestatin (chromogranin A344-364) is a novel cardiosuppressive agent: inhibition of isoproterenol and endothelin signaling in the frog heart.

本文引用的文献

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Early presence of phospholamban in developing a chick heart.
FEBS Lett. 1983 May 8;155(2):326-30. doi: 10.1016/0014-5793(82)80630-3.
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Calcium transport by cardiac sarcoplasmic reticulum and phosphorylation of phospholamban.心肌肌浆网的钙转运与受磷蛋白的磷酸化
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Phosphorylation of the sarcoplasmic reticulum and sarcolemma.肌浆网和肌膜的磷酸化
Annu Rev Physiol. 1982;44:401-23. doi: 10.1146/annurev.ph.44.030182.002153.
抑癌素(嗜铬粒蛋白A344 - 364)是一种新型的心脏抑制因子:对蛙心异丙肾上腺素和内皮素信号传导的抑制作用。
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Phospholamban-mediated stimulation of Ca2+ uptake in sarcoplasmic reticulum from normal and failing hearts.磷酸受磷蛋白介导的正常及衰竭心脏肌浆网对钙离子摄取的刺激作用
J Clin Invest. 1990 May;85(5):1698-702. doi: 10.1172/JCI114623.
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J Cell Sci. 1972 Jul;11(1):179-203. doi: 10.1242/jcs.11.1.179.
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Anal Biochem. 1971 Feb;39(2):462-77. doi: 10.1016/0003-2697(71)90436-2.
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Concerted regulation of cardiac sarcoplasmic reticulum calcium transport by cyclic adenosine monophosphate dependent and calcium--calmodulin-dependent phosphorylations.环磷酸腺苷依赖性磷酸化和钙-钙调蛋白依赖性磷酸化对心肌肌浆网钙转运的协同调节
Biochemistry. 1979 Nov 13;18(23):5150-7. doi: 10.1021/bi00590a019.
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Isolation of calcium pump system and purification of calcium ion-dependent ATPase from heart muscle.心肌中钙泵系统的分离及钙离子依赖性ATP酶的纯化。
Biochim Biophys Acta. 1976 Sep 7;443(3):468-84. doi: 10.1016/0005-2736(76)90466-1.