Al Saad Mouna, Shehadeh Amin, AlRyalat Saif A, Khawaldeh Tima, Shaqqour Rhagad, Al-Ani Ruqaya, Alqhaiwi Sereen B, Shehadeh Amal, Wahbeh Lina, Alrawashdeh Hamzeh M
Department of Special Surgery, Ophthalmology Division, School of Medicine, The University of Jordan, Jordan.
Department of Ophthalmology, Rotherham NHS Foundation Trust, Rotherham United Kingdom, England.
Saudi J Ophthalmol. 2025 Feb 7;39(1):60-64. doi: 10.4103/sjopt.sjopt_88_22. eCollection 2025 Jan-Mar.
To identify the possible predicting factors for developing astigmatism following penetrating keratoplasty, namely age, gender, laterality, preoperative indication for surgery, size of donor and recipient graft, and selective versus total sutures removal. Moreover, the duration of postoperative topical steroids use and if that surgery was the first graft or a redo surgery.
A retrospective cohort study which included data of patients who underwent penetrating keratoplasty at the University of Jordan Hospital. Multiple local and systemic perioperative risk factors were evaluated concerning developing postoperative astigmatism.
Three hundred and ninety-two eyes were included. Of those, 38.8% developed postoperative significant astigmatism. Significant astigmatism postkeratoplasty was found to be affected by preoperative diagnosis with corneal dystrophy being the most common indication associated with significant postoperative astigmatism. Significant astigmatism was significantly correlated with long-term topical steroid use, longer follow-up duration, and the first keratoplasty ( < 0.001). No correlation was found between significant astigmatism, age, and the time of suture removal.
Determination of the factors that influence the development of significant astigmatism is crucial. A long-term follow-up is necessary as the incidence of significant astigmatism increases with time.
确定穿透性角膜移植术后发生散光的可能预测因素，即年龄、性别、患侧、术前手术指征、供体和受体移植物大小以及选择性与完全缝线拆除。此外，术后局部使用类固醇的持续时间以及该手术是首次移植还是再次手术。
一项回顾性队列研究，纳入了约旦大学医院接受穿透性角膜移植术患者的数据。评估了与术后散光发生相关的多个局部和全身围手术期危险因素。
共纳入392只眼。其中，38.8%发生了术后显著散光。发现角膜移植术后显著散光受术前诊断影响，角膜营养不良是与术后显著散光相关最常见的指征。显著散光与长期局部使用类固醇、更长的随访时间以及首次角膜移植显著相关（<0.001）。未发现显著散光与年龄和缝线拆除时间之间存在相关性。
确定影响显著散光发生的因素至关重要。由于显著散光的发生率随时间增加，因此需要进行长期随访。
