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囊性纤维化相关骨病:筛查、诊断及治疗的最新进展

Cystic fibrosis-related bone disease: an update on screening, diagnosis, and treatment.

作者信息

Cobb Crystal, Wu Malinda, Tangpricha Vin

机构信息

Division of Endocrinology, Metabolism, and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.

Division of Endocrinology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

出版信息

Ther Adv Endocrinol Metab. 2025 Apr 2;16:20420188251328210. doi: 10.1177/20420188251328210. eCollection 2025.

Abstract

Cystic fibrosis-related bone disease (CFBD) is a common endocrinopathy in people living with cystic fibrosis (CF) that is complex and multifactorial in origin. People with CF experience high rates of progressive bone density loss and increased fracture risk. Focus on prevention and treatment of CFBD is of increasing importance in a now aging CF population. This review will discuss current practices in CFBD, gaps in knowledge, and potential future studies with the goal of advancing the clinical care of patients with CFBD.

摘要

囊性纤维化相关骨病(CFBD)是囊性纤维化(CF)患者中一种常见的内分泌病,其病因复杂且具有多因素性。CF患者经历着较高的进行性骨密度丧失率和骨折风险增加。在如今CF患者群体老龄化的情况下,关注CFBD的预防和治疗变得越来越重要。本综述将讨论CFBD的当前实践、知识空白以及潜在的未来研究,目标是推进CFBD患者的临床护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6369/11967205/fe2b84c4433d/10.1177_20420188251328210-fig1.jpg

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