Alonso M C, Torres A, Solana R, Manzanares M R, Garcia-Castellano J M, Peña J
Folia Biol (Praha). 1985;31(3):193-9.
The behaviour of committed CFU-GM bone marrow cells was investigated in leukaemic and preleukaemic AKR/J mice. The number of bone marrow CFU-GM decreased in the leukaemic stage of spontaneous AKR/J leukaemia. The addition of AKR/J leukaemic cells inhibited CFU-GM growth from normal target bone marrow. The bone marrow CFU-GM growth was also reduced in late preleukaemic AKR/J mice, whereas no modification in the CFU-GM number in early preleukaemic animals was found.
在白血病和白血病前期的AKR/J小鼠中研究了定向造血祖细胞集落生成单位（CFU-GM）骨髓细胞的行为。在自发的AKR/J白血病的白血病阶段，骨髓CFU-GM的数量减少。添加AKR/J白血病细胞可抑制正常靶骨髓中CFU-GM的生长。在白血病前期晚期的AKR/J小鼠中，骨髓CFU-GM的生长也减少，而在白血病前期早期的动物中未发现CFU-GM数量的改变。
