Greer F, Pusztai A
Digestion. 1985;32(1):42-6. doi: 10.1159/000199215.
Rats fed on diets containing kidney bean showed increased intestinal permeability to intravenously injected 125I-labelled rat serum proteins after an intragastric challenge with bean proteins. The enhanced accumulation of radioactive serum proteins in the lumen and walls of the small intestine indicated increased vascular permeability. It is suggested that dietary lectins may, at least in part, be responsible for this loss of serum proteins and thus contribute towards the overall toxicity of kidney bean proteins.
喂食含芸豆饮食的大鼠，在经胃内给予豆类蛋白刺激后，对静脉注射的125I标记大鼠血清蛋白的肠道通透性增加。放射性血清蛋白在小肠腔和肠壁中积累增多，表明血管通透性增加。有人提出，膳食凝集素可能至少部分导致了血清蛋白的这种损失，从而促成了芸豆蛋白的整体毒性。
