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经皮左心耳封堵术后的远程心包填塞

Remote Tamponade After Percutaneous Left Atrial Appendage Closure.

作者信息

Au Magdalene, Bobrowski David, Altin Eslem, Fam Neil, Angaran Paul, Ong Geraldine, Leong-Poi Howard, Yanagawa Bobby, Bagai Akshay

机构信息

Division of Cardiology, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

出版信息

JACC Case Rep. 2025 Apr 2;30(7):103388. doi: 10.1016/j.jaccas.2025.103388.

DOI:10.1016/j.jaccas.2025.103388
PMID:40185586
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12046869/
Abstract

BACKGROUND

The use of percutaneous left atrial appendage closure (LAAC) among patients with nonvalvular atrial fibrillation at high thromboembolic risk and contraindication to or high risk for bleeding with oral anticoagulation is increasing.

CASE SUMMARY

The authors present a case of acute hemorrhagic tamponade 7 months after LAAC. Intraoperative findings showed device-related microperforation of the LAA and erosion of the adjacent pulmonary artery.

DISCUSSION

Remote tamponade after LAAC has been reported with an incidence <1%, occurring more frequently in nitinol plug devices than in nitinol cage devices. Management ranges from conservative with cessation of antithrombotic agents to invasive with surgical repair.

TAKE-HOME MESSAGES: Remote tamponade after LAAC is a rare but potentially fatal complication. Routine use of cardiac computed tomography in addition to transesophageal echocardiography for preprocedural planning, especially for nitinol plug devices, can identify patients at risk of delayed tamponade and can guide device selection, modified implantation technique, or alternative management strategies.

摘要

背景

在具有高血栓栓塞风险且口服抗凝治疗存在禁忌或出血风险高的非瓣膜性心房颤动患者中,经皮左心耳封堵术(LAAC)的应用正在增加。

病例摘要

作者报告了1例LAAC术后7个月发生急性出血性心包填塞的病例。术中发现显示与器械相关的左心耳微穿孔及邻近肺动脉侵蚀。

讨论

LAAC术后迟发性心包填塞的发生率<1%,镍钛合金塞式器械比镍钛合金笼式器械更常发生。处理方法从停用抗血栓药物的保守治疗到手术修复的侵入性治疗不等。

经验教训

LAAC术后迟发性心包填塞是一种罕见但可能致命的并发症。除经食管超声心动图外,术前常规使用心脏计算机断层扫描进行术前规划,特别是对于镍钛合金塞式器械,可以识别有延迟心包填塞风险的患者,并可指导器械选择、改良植入技术或替代管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c004/12046869/bb057ce4016c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c004/12046869/ca520ab3cd0e/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c004/12046869/25ae5d9bed7b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c004/12046869/bb057ce4016c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c004/12046869/ca520ab3cd0e/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c004/12046869/25ae5d9bed7b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c004/12046869/bb057ce4016c/gr2.jpg

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本文引用的文献

1
Pericardial Effusion After Left Atrial Appendage Closure: Timing, Predictors, and Clinical Impact.左心耳封堵术后的心包积液:发生时间、预测因素和临床影响。
JACC Cardiovasc Interv. 2024 Jun 10;17(11):1295-1307. doi: 10.1016/j.jcin.2024.01.310. Epub 2024 May 22.
2
Delayed pericardial effusion or tamponade following left atrial appendage closure: A single-center experience.左心耳封堵术后迟发性心包积液或填塞:单中心经验。
J Formos Med Assoc. 2023 Aug;122(8):707-713. doi: 10.1016/j.jfma.2022.11.010. Epub 2022 Nov 30.
3
Pulmonary artery and left atrial appendage anatomical relationship using electrocardiogram- -gated computed tomography: An important aspect of left atrial appendage occlusion.
使用心电图门控计算机断层扫描技术观察肺动脉与左心耳的解剖关系:左心耳封堵的一个重要方面。
Cardiol J. 2021;28(2):342-344. doi: 10.5603/CJ.a2021.0024. Epub 2021 Feb 26.
4
Late presentation of left atrial appendage erosion and perforation by an Amplatzer™ Amulet™ closure device: a case report.Amplatzer™ Amulet™封堵器致左心耳侵蚀穿孔的迟发性表现:1例病例报告
Eur Heart J Case Rep. 2020 May 3;4(3):1-5. doi: 10.1093/ehjcr/ytaa079. eCollection 2020 Jun.
5
Left atrial appendage occlusion with the AMPLATZER Amulet device: periprocedural and early clinical/echocardiographic data from a global prospective observational study.应用 AMPLATZER Amulet 装置行左心耳封堵术:一项全球前瞻性观察研究的围术期和早期临床/超声心动图数据。
EuroIntervention. 2017 Sep 20;13(7):867-876. doi: 10.4244/EIJ-D-17-00493.
6
Left atrial appendage and pulmonary artery anatomic relationship by cardiac-gated computed tomography: Implications for late pulmonary artery perforation by left atrial appendage closure devices.心脏门控计算机断层扫描显示的左心耳与肺动脉的解剖关系:对左心耳封堵装置所致晚期肺动脉穿孔的启示
Heart Rhythm. 2016 Oct;13(10):2064-9. doi: 10.1016/j.hrthm.2016.07.015. Epub 2016 Jul 16.