Luther Lauren, Zhang Zhixin, James Sydney H, Zhang Luyu, Standridge Jennifer, Arnold Lauren, Condray Ruth, Allen Daniel N, Strauss Gregory P
Department of Psychology, University of Alabama at Birmingham, 1300 University Boulevard, Room 415, Birmingham, AL, 35233, USA.
Department of Psychology, University of Georgia, 125 Baldwin Street, Athens, GA, 30602, USA.
Schizophrenia (Heidelb). 2025 Apr 4;11(1):56. doi: 10.1038/s41537-025-00602-4.
Limited negative symptoms treatment effectiveness may result from environmental resource deprivation that is a barrier for performing goal-directed, recreational, and social activities. This study showed that environmental resource deprivation in the home environment was greater for people with schizophrenia (n = 39) than 32 demographically-matched healthy controls (CN). Greater environmental resource reductions for performing goal-directed, recreational, and social activities were associated with greater negative symptoms, even after controlling for income and secondary negative symptom factors (depression, positive symptoms).
有限的阴性症状治疗效果可能源于环境资源匮乏,这是进行目标导向、娱乐和社交活动的障碍。本研究表明,精神分裂症患者(n = 39)家庭环境中的环境资源匮乏程度高于32名人口统计学匹配的健康对照者(CN)。即使在控制了收入和继发性阴性症状因素(抑郁、阳性症状)之后,进行目标导向、娱乐和社交活动时更大程度的环境资源减少与更严重的阴性症状相关。