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急性肾损伤成人患者液体状态的临床评估:一项范围综述

Clinical Assessment of Fluid Status in Adults With Acute Kidney Injury: A Scoping Review.

作者信息

Nagalingam Karen, Whiting Lisa, Farrington Ken, Migliozzi Janet, Pattison Natalie

机构信息

University of Hertfordshire, Hatfield, UK.

Lister Hospital, East and North Hertfordshire NHS Trust, Stevenage, UK.

出版信息

J Ren Care. 2025 Jun;51(2):e70014. doi: 10.1111/jorc.70014.

Abstract

BACKGROUND

Acute kidney injury refers to sudden, potentially reversible, reduction in kidney function. Hypovolaemia is commonly the major risk factor. When acute kidney injury is established, fluid can accumulate leading to fluid overload. Undertaking a rigorous fluid assessment is vital in the management of a patient in hospital with acute kidney injury, as insufficient or excessive fluid can lead to increased morbidity and mortality.

OBJECTIVES

The aim of this scoping review is to identify which clinical assessments are useful when undertaking fluid assessment in a patient with acute kidney injury, and to identify signs and symptoms of fluid overload or dehydration in patients in hospital with acute kidney injury.

DESIGN

The JBI methodology for scoping reviews was followed and reported using the PRISMA-ScR checklist. PubMed, CINAHL Plus and SCOPUS were searched for research papers relating to the signs and symptoms or fluid assessments in patients with acute kidney injury.

RESULTS

Fifteen research papers were identified with four key areas being: Fluid balance/urine output and weight; early warning scores; clinical signs and symptoms; holistic assessment. The primary studies included in this scoping review have shown that hypovolaemia may be indicated by low blood pressure, orthostatic hypotension, low Mean Arterial Pressure, elevated heart rate, prolonged capillary refill time on the sternum (> 4.5 s) and subjectively reported cold peripheries. With clinical symptoms including dry mouth, increased thirst and dry skin. Accurate documentation of urine output and fluid balance is crucial in determining fluid status.

CONCLUSION

The assessment of fluid should be holistic and include history taking, diagnosis, blood tests and associated clinical signs and symptoms.

摘要

背景

急性肾损伤是指肾功能突然出现的、可能可逆的减退。血容量不足通常是主要危险因素。急性肾损伤确诊后,液体可能会蓄积,导致液体超负荷。对急性肾损伤住院患者进行严格的液体评估至关重要,因为液体不足或过多都会导致发病率和死亡率增加。

目的

本综述的目的是确定在对急性肾损伤患者进行液体评估时哪些临床评估是有用的,并确定急性肾损伤住院患者液体超负荷或脱水的体征和症状。

设计

遵循JBI综述方法,并使用PRISMA-ScR清单进行报告。在PubMed、CINAHL Plus和SCOPUS中检索与急性肾损伤患者的体征和症状或液体评估相关的研究论文。

结果

共识别出15篇研究论文,涉及四个关键领域:液体平衡/尿量和体重;早期预警评分;临床体征和症状;整体评估。本综述纳入的主要研究表明,血容量不足可能表现为低血压、体位性低血压、平均动脉压降低、心率升高、胸骨毛细血管再充盈时间延长(>4.5秒)以及主观感觉外周发冷。临床症状包括口干、口渴增加和皮肤干燥。准确记录尿量和液体平衡对于确定液体状态至关重要。

结论

液体评估应是全面的,包括病史采集、诊断、血液检查以及相关的临床体征和症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c52c/11971954/6a54bf97fb6d/JORC-51-0-g001.jpg

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