Kaveh Mania, Moghadam Maryam Nakhaee, Safari Mojtaba, Chaichian Shahla, Kashi Abolfazl Mehdizadeh, Afshari Mehdi, Sadegi Kambiz
Department of Obstetrics and Gynecology, School of Medicine, Amir Al Momenin Hospital, Zabol University of Medical Sciences, Zabol, Iran.
Iranian Scientific Society of Minimally Invasive Gynecology, Tehran, Iran.
Arch Gynecol Obstet. 2025 May;311(5):1415-1421. doi: 10.1007/s00404-025-07999-4. Epub 2025 Apr 6.
Endometriosis is one of the most common chronic diseases in women, with a prevalence of up to 10%. The disease particularly affects women of reproductive age. Endometriosis has a significant impact on the patient's quality of life (QoL). In the current study, we aimed to evaluate the role of early diagnosis of endometriosis on patients' QoL.
In this longitudinal prospective study, 205 women with endometriosis who were referred to the gynecology department of Amir al-Mominin Hospital (Zabol-Iran) in 2021 were evaluated. Patients were divided into two groups based on the time of diagnosis, including early diagnosis and late diagnosis. An Endometriosis Health Profile (EHP) questionnaire was used to collect information about QoL before and 18 months after treatment. Data were analyzed using SPSSv.26 software and significance level was considered less than 0.05.
In both groups with early and late diagnosis, the QoL scores improved without significant difference (p = 0.303). There was a significant difference between lower stages (1 and 2) and higher stages (3 and 4) in terms of treatment effects on patients' QoL, and higher stages of endometriosis affected patients' QoL before and after treatment more than lower stages (P values < 0.05).
Early or late diagnosis of endometriosis doesn't affect patients' QoL and patients benefit from treatment regardless of the time of diagnosis.
子宫内膜异位症是女性最常见的慢性疾病之一，患病率高达10%。该疾病尤其影响育龄女性。子宫内膜异位症对患者的生活质量（QoL）有重大影响。在本研究中，我们旨在评估子宫内膜异位症早期诊断对患者生活质量的作用。
在这项纵向前瞻性研究中，对2021年转诊至阿米尔·穆民医院（伊朗扎博勒）妇科的205例子宫内膜异位症女性患者进行了评估。根据诊断时间将患者分为两组，包括早期诊断组和晚期诊断组。使用子宫内膜异位症健康概况（EHP）问卷收集治疗前和治疗后18个月的生活质量信息。使用SPSSv.26软件进行数据分析，显著性水平设定为小于0.05。
在早期诊断组和晚期诊断组中，生活质量评分均有所改善，差异无统计学意义（p = 0.303）。就治疗对患者生活质量的影响而言，较低分期（1期和2期）与较高分期（3期和4期）之间存在显著差异，子宫内膜异位症较高分期对患者治疗前后生活质量的影响大于较低分期（P值<0.05）。
子宫内膜异位症的早期或晚期诊断不影响患者的生活质量，无论诊断时间如何，患者均可从治疗中获益。
