Soares João, Craveiro Costa Ricardo, Cardoso Rúben, Pinto Joana, Carvalho Sílvia, Castendo Ramos Leonor
Dermatology, Hospital Pediátrico, Unidade Local de Saúde de Coimbra, Coimbra, PRT.
Pediatrics, Hospital Pediátrico, Unidade Local de Saúde de Coimbra, Coimbra, PRT.
Cureus. 2025 Mar 5;17(3):e80097. doi: 10.7759/cureus.80097. eCollection 2025 Mar.
Infantile hemangiomas are the most common soft tissue tumors in infancy, most following a benign and predictable course. However, some hemangiomas, particularly those in the lower body, can indicate underlying syndromic anomalies, as seen in lower body hemangiomas and other cutaneous defects, urogenital anomalies, ulceration, myelopathy, bony deformities, anorectal malformations, arterial anomalies, and renal anomalies (LUMBAR) syndrome. This report presents the case of a term infant with a large superficial ulcerated sacral hemangioma and associated spinal dysraphism, including tethered cord, partial sacral agenesis, and intraspinal lipoma. The early multidisciplinary evaluation confirmed the diagnosis of LUMBAR syndrome, and the patient underwent surgical management of cutaneous discontinuities and initiated oral propranolol. Propranolol was effective in resolving the ulcerated component of the hemangioma. This case highlights the importance of recognizing lower body hemangiomas as markers for potential underlying anomalies, emphasizing the role of early diagnosis, comprehensive imaging, and multidisciplinary care in optimizing outcomes for this rare but complex syndrome.
婴儿血管瘤是婴儿期最常见的软组织肿瘤，大多数病程呈良性且可预测。然而，一些血管瘤，尤其是下半身的血管瘤，可能提示潜在的综合征性异常，如下半身血管瘤合并其他皮肤缺损、泌尿生殖系统异常、溃疡、脊髓病、骨骼畸形、肛门直肠畸形、动脉异常和肾脏异常（LUMBAR）综合征。本报告介绍了一名足月儿，患有巨大浅表溃疡性骶部血管瘤及相关脊柱发育异常，包括脊髓拴系、部分骶骨发育不全和椎管内脂肪瘤。早期多学科评估确诊为LUMBAR综合征，患者接受了皮肤缺损的手术治疗，并开始口服普萘洛尔。普萘洛尔有效解决了血管瘤的溃疡部分。该病例强调了将下半身血管瘤识别为潜在潜在异常标志物的重要性，强调了早期诊断、全面成像和多学科护理在优化这种罕见但复杂综合征治疗结果中的作用。
