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儿童分期等蠕动胃管食管置换术:十年经验

Staged Isoperistaltic Gastric Tube Esophageal Replacement in Children: A Decade of Experience.

作者信息

Rawat J D, Tyagi Nirpex, Singh Sudhir

机构信息

Department of Pediatric Surgery, KGMU, Lucknow, Uttar Pradesh, India.

出版信息

J Indian Assoc Pediatr Surg. 2025 Mar-Apr;30(2):177-182. doi: 10.4103/jiaps.jiaps_188_24. Epub 2025 Jan 2.

Abstract

CONTEXT

Esophageal atresia (EA), with or without tracheoesophageal fistula (TEF), is a rare congenital anomaly. Long-gap esophageal atresia (LGEA) and failed primary repair of TEF often necessitate esophageal replacement in children. This study assesses the outcomes of staged isoperistaltic esophageal replacement using a gastric tube, particularly in resource-limited settings.

AIMS

The aim of this study was to evaluate the outcomes of staged isoperistaltic esophageal replacement using a gastric tube in children with LGEA and failed primary repair of TEF, particularly in resource-limited settings.

SETTINGS AND DESIGN

The study was conducted tertiary care hospital, an observational design, spanning 10 years from January 2012 to January 2022.

METHODS

This study, spanning 10 years (January 2012 to January 2022), focused on pure EA and LGEA with TEF. The three-stage approach included neonatal gastrostomy and esophagostomy, the creation of an isoperistaltic gastric tube at around 10 kg body weight, retrosternal tunneling, and subsequent closure of the cervical esophagostomy. Data on gender, weight, age, complications, gastric emptying, esophageal mucosal status, gastroesophageal reflux, and growth and nutritional status were analyzed.

STATISTICAL ANALYSIS USED

The study primarily utilized descriptive statistics to analyze the data. This included reporting means with standard deviations for continuous variables such as weight and age at the time of the second surgery.

RESULTS

Twenty-seven cases were studied, with a male-to-female ratio of 3:1. At the second surgery, the mean weight was 9.52 ± 0.56 kg, and the mean age was 8.5 ± 1.25 months. Four cases had minor cervical anastomotic leaks, which were managed conservatively. No postoperative ventilator support was needed. Esophageal stenosis occurred in one case and was managed with endoscopic dilatation. No delayed gastric emptying or Barrett's esophagus was observed. Growth and nutritional assessments were normal. One mortality occurred due to postoperative bronchospasm.

CONCLUSION

This 10-year study shows that staged isoperistaltic esophageal replacement with a gastric tube is a feasible option for managing EA and LGEA with TEF in resource-limited settings. The technique had low complication rates and supported normal growth and nutrition during follow-up.

摘要

背景

食管闭锁(EA),伴或不伴气管食管瘘(TEF),是一种罕见的先天性畸形。长间隙食管闭锁(LGEA)和TEF一期修复失败常使儿童需要进行食管置换。本研究评估了使用胃管分期进行等蠕动食管置换的效果,尤其是在资源有限的环境中。

目的

本研究的目的是评估在LGEA和TEF一期修复失败的儿童中,使用胃管分期进行等蠕动食管置换的效果,尤其是在资源有限的环境中。

设置与设计

该研究在一家三级护理医院进行,采用观察性设计,时间跨度为2012年1月至2022年1月的10年。

方法

本研究历时10年(2012年1月至2022年1月),聚焦于单纯EA和伴有TEF的LGEA。三阶段方法包括新生儿胃造口术和食管造口术,在体重约10kg时制作等蠕动胃管,胸骨后隧道形成,以及随后关闭颈部食管造口。分析了性别、体重、年龄、并发症、胃排空、食管黏膜状况、胃食管反流以及生长和营养状况的数据。

所用统计分析方法

该研究主要采用描述性统计方法分析数据。这包括报告连续变量(如第二次手术时的体重和年龄)的均值及标准差。

结果

共研究了27例病例,男女比例为3:1。第二次手术时,平均体重为9.52±0.56kg,平均年龄为8.5±1.25个月。4例出现轻微的颈部吻合口漏,经保守治疗。术后无需呼吸机支持。1例发生食管狭窄,经内镜扩张治疗。未观察到胃排空延迟或巴雷特食管。生长和营养评估正常。1例因术后支气管痉挛死亡。

结论

这项为期10年的研究表明,在资源有限的环境中,使用胃管分期进行等蠕动食管置换是治疗EA和伴有TEF的LGEA的一种可行选择。该技术并发症发生率低,在随访期间支持正常生长和营养。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8eb8/11968038/5c5f14388df5/JIAPS-30-177-g001.jpg

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