Choudhury Subhasis Roy, Yadav Partap Singh, Khan Niyaz Ahmed, Shah Shalu, Debnath Pinaki Ranjan, Kumar Virendra, Chadha Rajiv
Department of Pediatric Surgery, Lady Hardinge Medical College and Kalawati Saran Children's Hospital, New Delhi, India.
Department of Paediatric Intensive Care, Lady Hardinge Medical College and Kalawati Saran Children's Hospital, New Delhi, India.
J Indian Assoc Pediatr Surg. 2016 Jul-Sep;21(3):110-4. doi: 10.4103/0971-9261.182582.
The aim of this study was to report the results of pediatric esophageal substitution by gastric pull-up (GPU) and gastric tube (GT) from a tertiary care pediatric center.
Retrospective analysis of the surgical techniques, results, complications, and final outcome of all pediatric patients who underwent esophageal substitution in a single institution was performed.
Twenty-four esophageal substitutions were performed over 15-year period. The indications were pure esophageal atresia (EA)-19, EA with distal trachea-esophageal fistula-2, EA with proximal pouch fistula-1, and esophageal stricture in two patients. Mean age and weight at operation were 17 months and 9.5 kg, respectively. GPU was the most common procedure (19) followed by reverse GT (4) and gastric fundal tube (1). Posterior mediastinal and retrosternal routes were used in 17 and 7 cases, respectively. Major complications included three deaths in GPU cases resulting from postoperative tachyarrhythmias leading to cardiac arrest, cervical anastomotic leak-17, and anastomotic stricture in six cases. Perioperative tachyarrhythmias (10/19) and transient hypertension (2/19) were observed in GPU patients, and they were managed with beta blocker drugs. Postoperative ventilation in Intensive Care Unit was performed for all GPU, but none of the GT patients. Follow-up ranged from 6 months to 15 years that showed short-term feeding difficulties and no major growth-related problems.
Perioperative tachyarrhythmias are common following GPU which mandates close intensive care monitoring with ventilation and judicious use of beta blocking drugs. Retrosternal GT with a staged neck anastomosis can be performed without postoperative ventilation.
本研究旨在报告一家三级儿科护理中心采用胃上提术(GPU)和胃管(GT)进行小儿食管替代的结果。
对在单一机构接受食管替代的所有小儿患者的手术技术、结果、并发症及最终结局进行回顾性分析。
在15年期间共进行了24例食管替代手术。适应证包括单纯食管闭锁(EA)19例、合并远端气管食管瘘的EA 2例、合并近端袋状瘘的EA 1例以及2例食管狭窄。手术时的平均年龄和体重分别为17个月和9.5千克。GPU是最常用的手术方式(19例),其次是反向GT(4例)和胃底管(1例)。分别有17例和7例采用后纵隔途径和胸骨后途径。主要并发症包括GPU病例中有3例因术后快速心律失常导致心脏骤停死亡、17例颈部吻合口漏以及6例吻合口狭窄。GPU患者中观察到围手术期快速心律失常(10/19)和短暂性高血压(2/19),并使用β受体阻滞剂进行处理。所有GPU患者术后均在重症监护病房进行通气,而GT患者均未进行。随访时间为6个月至15年,显示存在短期喂养困难,但无重大生长相关问题。
GPU术后围手术期快速心律失常很常见,这就要求密切的重症监护监测、通气以及谨慎使用β受体阻滞剂。胸骨后GT分期进行颈部吻合可不进行术后通气。