Soltani Kiarash, Keshavarz Elham, Pouya Ensi Khalili, Jamali Razieh, Langroudi Taraneh Faghihi, Haseli Sara
Department of Radiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Radiology, Shahid Beheshti University of Medical Sciences, Mahdieh hospital, Tehran, Iran.
Medicine (Baltimore). 2025 Apr 4;104(14):e41933. doi: 10.1097/MD.0000000000041933.
The diagnostic role of Doppler ultrasonography regarding Hashimoto thyroiditis (HT) is not fully established. We examined intraparenchymal resistive index (RI) as a Doppler parameter, thyroidal vascularity and other Gray-Scale findings in adults with HT in order to evaluate the clinical feasibility of RI in the diagnosis of this disease. The study included 48 women aged 20 to 50 years who had recently been diagnosed with HT. These participants, who were either euthyroid or sub-clinically hypothyroid during the study period, underwent sonographic examination. Thyroid glands were classified into 4 distinct patterns, using the Color Doppler Scale introduced by Schultz et al and also based on Sostre and Reyes Gray-Scale Grading System they were classified into 4 Grades. Intraparenchymal RIs were obtained in 2 locations within each lobe of the thyroid gland. Gray-Scale findings were compared to Doppler findings (RI). Also, intraparenchymal RIs were obtained in 45 healthy adults as a control group. The mean RI values were determined by calculating the mean of the RI measurements obtained from both lobes of each participant in the patient and control groups. The mean RI value was found to be 0.57 ± 0.05 (range 0.5-0.7) cm/s in patient group and 0.54 ± 0.05 (range 0.47-0.7) cm/s in control group. The results were distributed as follows: pattern 0 was observed in 22 cases, pattern I in 15 cases, pattern II in 6 cases, and pattern III in 5 cases. The mean RI values for patients with normal or nearly normal Gray-Scale findings (n = 13) and those with more pronounced Gray-Scale changes (n = 35) showed no significant difference. However, both groups exhibited higher mean RI values compared to the normal adults in the control group. The results highlight that the RI could be an effective and sensitive tool for diagnosing HT through Doppler ultrasonography.
多普勒超声检查对桥本甲状腺炎（HT）的诊断作用尚未完全明确。我们将实质内阻力指数（RI）作为多普勒参数，研究了成年HT患者的甲状腺实质内血管情况及其他灰阶表现，以评估RI在该疾病诊断中的临床可行性。该研究纳入了48名年龄在20至50岁之间、近期被诊断为HT的女性。这些参与者在研究期间甲状腺功能正常或处于亚临床甲状腺功能减退状态，均接受了超声检查。采用Schultz等人提出的彩色多普勒分级标准，甲状腺被分为4种不同模式；同时基于Sostre和Reyes灰阶分级系统，甲状腺被分为4级。在甲状腺每侧叶的两个位置获取实质内RI。将灰阶表现与多普勒检查结果（RI）进行比较。此外，选取45名健康成年人作为对照组，同样在其甲状腺每侧叶的两个位置获取实质内RI。通过计算患者组和对照组中每位参与者两侧叶RI测量值的平均值来确定平均RI值。患者组的平均RI值为0.57±0.05（范围0.5 - 0.7）cm/s，对照组为0.54±0.05（范围0.47 - 0.7）cm/s。结果分布如下：模式0有22例，模式I有15例，模式II有6例，模式III有5例。灰阶表现正常或接近正常的患者（n = 13）与灰阶变化更明显的患者（n = 35）的平均RI值无显著差异。然而，与对照组的正常成年人相比，两组的平均RI值均更高。结果表明，RI可能是通过多普勒超声诊断HT的一种有效且敏感的工具。
