Leonhardi G, Klähn K H, Gürenci J
MMW Munch Med Wochenschr. 1977 Jan 14;119(2):43-6.
Extensive investigations form 1962 to 1973 on 23 patients with porphyria cutanea tarda are reported. Two collectives of patients with different treatments are compared. One collective was treated conventionally with "liver therapy, abstinence from alcohol, and rest in bed", the other collective with "phlebotomy, abstinence from alcohol, and rest in bed". Both collectives showed a nearly equal decrease of uroporphyrin excretion. The unfavourable effect of alcohol in this disease was confirmed. In the post-observation period, minimal excretion of uroporphyrin was found to be more frequent and to persist longer in the collective treated by phlebotomy. In this collective, abstinence from alcohol was more consistently adhered to.
报告了1962年至1973年对23例迟发性皮肤卟啉病患者进行的广泛调查。比较了两组接受不同治疗的患者。一组采用“肝脏疗法、戒酒和卧床休息”的传统治疗方法,另一组采用“放血疗法、戒酒和卧床休息”。两组的尿卟啉排泄量下降程度几乎相同。证实了酒精对这种疾病的不良影响。在观察后期,发现放血治疗组尿卟啉排泄量最低的情况更频繁且持续时间更长。在该组中,戒酒的坚持情况更好。