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改善耳鼻喉科手术后多模式镇痛药物的使用——一家机构9000例患者的经验

Improving Multimodal Analgesic Use After Otolaryngologic Surgery-A Single-Institution Experience of 9000 Patients.

作者信息

Plonowska-Hirschfeld Karolina A, Saroya Jasmeet, Herrera Jose, Chang Jolie L, Goldberg Andrew N, Seth Rahul, Durr Megan L

机构信息

Department of Otolaryngology-Head and Neck Surgery Washington University in St. Louis St. Louis Missouri USA.

Department of Otolaryngology-Head and Neck Surgery University of California San Francisco San Francisco California USA.

出版信息

OTO Open. 2025 Apr 7;9(2):e70106. doi: 10.1002/oto2.70106. eCollection 2025 Apr-Jun.

DOI:10.1002/oto2.70106
PMID:40196217
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11973581/
Abstract

OBJECTIVE

This study aims to assess a quality improvement intervention to decrease opiate prescriptions at discharge and improve patient access to multimodal analgesics (MMA) after otolaryngologic surgery.

STUDY DESIGN

Longitudinal quality improvement initiative with retrospective prescription trend review and prospective patient questionnaire collection.

SETTING

An academic medical center.

METHODS

Opioid, acetaminophen, and non-steroidal anti-inflammatory drug (NSAID) discharge prescriptions after otolaryngologic procedures were reviewed. Two annual department-wide workshops were carried out to review the literature on published MMA protocols and develop standardized post-operative pain medication instructions to reduce opioid use. Concurrently, a patient survey was distributed to evaluate discharge pain medication use and satisfaction with pain control.

RESULTS

Discharge pain medications were reviewed for 9064 procedures between January 2021 and May 2024. After the interventions above, the percentage of patients receiving opioids at discharge decreased from 61.4% to 46.8% ( < .00001). Concurrently, acetaminophen and NSAID discharge prescriptions increased from 24.3% and 10.2% to 67.4% and 46.1%, respectively (both  < .00001). Among 100 patients surveyed, satisfaction with post-operative pain control was high before and after the implementation of standardized discharge instructions, even though fewer post-intervention patients received opioids at discharge (49.1% compared to 76.6% pre-intervention,  = .007). Notably, 27% of patients prescribed opioids reported not taking them and 23% reported saving unused opioids for future use.

CONCLUSION

Implementation of standardized post-operative pain medication instructions at discharge after otolaryngologic procedures led to a substantial decrease in opioids prescribed while maintaining patient satisfaction with post-operative pain management. A significant proportion of patients reported saving unused opioids for future use despite standardized safe disposal instructions.

摘要

目的

本研究旨在评估一项质量改进干预措施,以减少出院时的阿片类药物处方,并改善耳鼻喉科手术后患者获得多模式镇痛药物(MMA)的机会。

研究设计

采用纵向质量改进计划,回顾性分析处方趋势,并前瞻性收集患者问卷。

研究地点

一家学术医疗中心。

方法

对耳鼻喉科手术后出院时开具的阿片类药物、对乙酰氨基酚和非甾体抗炎药(NSAID)处方进行审查。每年举办两次全科室研讨会,回顾已发表的MMA方案相关文献,并制定标准化的术后疼痛药物使用说明,以减少阿片类药物的使用。同时,发放患者调查问卷,评估出院时疼痛药物的使用情况以及对疼痛控制的满意度。

结果

对2021年1月至2024年5月期间的9064例手术的出院疼痛药物处方进行了审查。经过上述干预措施后,出院时接受阿片类药物治疗的患者比例从61.4%降至46.8%(P<0.00001)。同时,对乙酰氨基酚和NSAID出院处方分别从24.3%和10.2%增至67.4%和46.1%(均P<0.00001)。在接受调查的100例患者中,尽管干预后出院时接受阿片类药物治疗的患者较少(干预后为49.1%,干预前为76.6%,P=0.007),但在实施标准化出院说明前后,患者对术后疼痛控制的满意度都很高。值得注意的是,27%开具阿片类药物处方的患者报告未服用,23%报告将未使用的阿片类药物留存以备将来使用。

结论

耳鼻喉科手术后出院时实施标准化的术后疼痛药物使用说明,在保持患者对术后疼痛管理满意度的同时,使开具的阿片类药物大幅减少。尽管有标准化的安全处置说明,但仍有相当比例的患者报告将未使用的阿片类药物留存以备将来使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14e6/11973581/9630d768bcd5/OTO2-9-e70106-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14e6/11973581/efa01e2ac77b/OTO2-9-e70106-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14e6/11973581/572ce819b1ee/OTO2-9-e70106-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14e6/11973581/9630d768bcd5/OTO2-9-e70106-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14e6/11973581/efa01e2ac77b/OTO2-9-e70106-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14e6/11973581/572ce819b1ee/OTO2-9-e70106-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14e6/11973581/9630d768bcd5/OTO2-9-e70106-g003.jpg

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本文引用的文献

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OTO Open. 2023 Mar 14;7(1):e17. doi: 10.1002/oto2.17. eCollection 2023 Jan-Mar.
2
Postoperative opioid-prescribing practices in otolaryngology: Evidence-based guideline outcomes.耳鼻喉科术后阿片类药物处方实践:循证指南结果
Laryngoscope Investig Otolaryngol. 2022 Dec 16;8(1):313-321. doi: 10.1002/lio2.990. eCollection 2023 Feb.
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Surgical Patient Compliance With Healthcare Facility-Provided In-home Opioid Disposal Products: A Systematic Review.
手术患者对医疗机构提供的家用阿片类药物处置产品的遵从性:系统评价。
J Nurs Adm. 2022 Jan 1;52(1):35-41. doi: 10.1097/NNA.0000000000001100.
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Multimodal Analgesia in Head and Neck Free Flap Reconstruction: A Systematic Review.头颈部游离皮瓣重建中的多模式镇痛:一项系统综述。
Otolaryngol Head Neck Surg. 2022 May;166(5):820-831. doi: 10.1177/01945998211032910. Epub 2021 Aug 10.
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Increasing the use of multimodal analgesia during adult surgery in a tertiary academic anaesthesia department.提高成人手术中多模式镇痛的应用。
BMJ Open Qual. 2021 Jul;10(3). doi: 10.1136/bmjoq-2020-001320.
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Prescription opioids are commonly unused after ambulatory head and neck surgeries: Opioids prescription presence and size has no effect on patient satisfaction with pain control.门诊头颈外科手术后,处方阿片类药物通常未被使用:阿片类药物的处方开具情况及剂量对患者疼痛控制满意度没有影响。
Am J Otolaryngol. 2021 Nov-Dec;42(6):103093. doi: 10.1016/j.amjoto.2021.103093. Epub 2021 May 28.
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JAMA. 2021 May 25;325(20):2040. doi: 10.1001/jama.2021.7464.
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