三种连续血糖监测系统所得血糖指标的比较分析
A Comparative Analysis of Glycemic Metrics Derived From Three Continuous Glucose Monitoring Systems.
作者信息
Freckmann Guido, Wehrstedt Stephanie, Eichenlaub Manuel, Pleus Stefan, Link Manuela, Jendrike Nina, Öter Sükrü, Brandt Derek, Haug Cornelia, Waldenmaier Delia
机构信息
Institut für Diabetes-Technologie, Forschungs- und Entwicklungsgesellschaft mbH an der Universität Ulm, Ulm, Germany.
Diabetes Center Berne, Berne, Switzerland.
出版信息
Diabetes Care. 2025 Jul 1;48(7):1213-1217. doi: 10.2337/dc25-0129.
OBJECTIVE
This study analyzed the differences in continuous glucose monitoring (CGM)-derived metrics among three current-generation systems and evaluated their impact on therapeutic decision-making.
RESEARCH DESIGN AND METHODS
Twenty-three participants wore the FreeStyle Libre 3, Dexcom G7, and Medtronic Simplera CGM systems for 14 days in parallel. CGM metrics were calculated for each participant and CGM system separately.
RESULTS
The apparent glucose profile was influenced by the used CGM system, resulting in substantially different glycemic metrics among the three systems. Agreement between FreeStyle Libre 3 and Dexcom G7 was higher than with Medtronic Simplera, which showed lower glucose levels, on average. There were marked intraparticipant discrepancies that would have resulted in different therapeutic recommendations.
CONCLUSIONS
The CGM systems indicated discordant glycemic metrics, which should be considered in diabetes therapy. Different CGM systems should provide the same glucose readings and CGM-derived metrics when used by the same person.
目的
本研究分析了三种新一代连续血糖监测（CGM）系统在CGM衍生指标上的差异，并评估了它们对治疗决策的影响。
研究设计与方法
23名参与者同时佩戴FreeStyle Libre 3、Dexcom G7和美敦力Simplera CGM系统14天。分别为每位参与者和每个CGM系统计算CGM指标。
结果
所使用的CGM系统会影响表观血糖曲线，导致三个系统之间的血糖指标存在显著差异。FreeStyle Libre 3与Dexcom G7之间的一致性高于与美敦力Simplera的一致性，美敦力Simplera平均显示的血糖水平较低。参与者内部存在明显差异，这可能会导致不同的治疗建议。
结论
CGM系统显示出血糖指标不一致，这在糖尿病治疗中应予以考虑。不同的CGM系统在被同一人使用时应提供相同的血糖读数和CGM衍生指标。
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