Alyaquobi Fatma M, Alhakamani Fatma, Alsabari Mohammed, Althuhli Khalsa, AlMahroqi Moza Al, Al-Jardani Amina, Al-Yazidi Mohammed, Rawahi Bader Al, Maani Amal Al
TB and Acute Respiratory Section, Department of Communicable Disease, Center for Disease Control and Prevention, Ministry of Health, Muscat, Oman.
Environmental and Occupational Health, Center for Disease Control and Prevention, Ministry of Health, Muscat, Oman.
IJID Reg. 2025 Mar 19;14(Suppl 2):100614. doi: 10.1016/j.ijregi.2025.100614. eCollection 2025 Mar.
This study aimed to outline the process of implementation of latent tuberculosis (TB) infection (LTBI) screening among migrants using interferon-γ release assay (IGRA), describe the LTBI treatment protocol and cascade of care, and highlight success factors and challenges.
This is a description of the process of implementation of screening of TB infection through a medical fitness program for residency, using primary care treatment module and short regimen.
Before 2018, expatriates seeking residency employment in Oman undergo two-step medical fitness examination process that mainly rely on chest X-ray (CXR) before arrival and physical examination after arrival, with 15% random sample repeated. In 2018, Oman implemented CXR screening for all alongside symptom checks. With further surge of TB cases after COVID-19, screening using IGRA was introduced through a medical fitness program in 2024. Those who are IGRA-positive or indeterminate will proceed to CXR with subsequent referral to primary care for short regimen treatment (3 months of daily rifampicin plus isoniazid and pyridoxine) if eligible.
Oman aims to achieve sustainability through establishing an integrated LTBI screening for migrants within the residency medical fitness program using integrated electronic system, highly sensitive test, public private model (under government regulation), and high throughput testing methods. Treatment using a short regimen (3 months of daily rifampicin plus isoniazid) through primary care will improve treatment adherence, improve outcome, and reduce TB incidence.
本研究旨在概述使用干扰素-γ释放试验（IGRA）对移民进行潜伏性结核感染（LTBI）筛查的实施过程，描述LTBI治疗方案和照护流程，并突出成功因素和挑战。
这是一项关于通过居住医学健康计划实施结核感染筛查过程的描述，采用初级保健治疗模块和短程治疗方案。
2018年之前，在阿曼寻求居住就业的外籍人士在抵达前主要依靠胸部X光检查（CXR），抵达后进行体格检查，进行两步医学健康检查，15%的随机样本会重复检查。2018年，阿曼除了症状检查外，还对所有人实施了CXR筛查。在2019冠状病毒病后结核病例进一步激增的情况下，2024年通过一项医学健康计划引入了使用IGRA的筛查。IGRA检测呈阳性或结果不确定的人将进行CXR检查，随后如果符合条件，将被转诊至初级保健机构接受短程治疗（每日服用利福平、异烟肼和吡哆醇3个月）。
阿曼的目标是通过在居住医学健康计划中为移民建立综合的LTBI筛查来实现可持续性，采用综合电子系统、高灵敏度检测、公私合作模式（在政府监管下）和高通量检测方法。通过初级保健使用短程治疗方案（每日服用利福平加异烟肼3个月）将提高治疗依从性、改善治疗效果并降低结核病发病率。
