Harris Jenine K, Solomon Erin D, Baldwin Kari, Baker Lauren L, Chin Eu Gene, DuBois James M
Brown School, Washington University in St. Louis, USA.
Division of General Medicine & Geriatrics, Washington University in St Louis, USA.
J Clin Transl Sci. 2025 Mar 24;9(1):e60. doi: 10.1017/cts.2025.38. eCollection 2025.
The attitudes toward genomics and precision medicine (AGPM) measure examines attitudes toward activities such as genetic testing, gene editing, and biobanking. This is a useful tool for research on the ethical, legal, and social implications of genomics, a major program within the National Institutes of Health. We updated the AGPM to explore controversies over mRNA vaccines. This brief report examines the factor structure of the updated AGPM using a sample of 4939 adults in the USA. The updated AGPM's seven factors include health benefits, knowledge benefits, and concerns about the sacredness of life, privacy, gene editing, mRNA vaccines, and social justice.
基因组学与精准医学态度（AGPM）量表用于考察人们对基因检测、基因编辑和生物样本库等活动的态度。这是研究基因组学的伦理、法律和社会影响的有用工具，基因组学是美国国立卫生研究院的一个重要项目。我们对AGPM进行了更新，以探讨有关mRNA疫苗的争议。本简要报告使用美国4939名成年人的样本，研究了更新后的AGPM的因子结构。更新后的AGPM的七个因子包括健康益处、知识益处，以及对生命神圣性、隐私、基因编辑、mRNA疫苗和社会正义的担忧。
